Search tips
Search criteria 


Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
Proc R Soc Med. 1970 April; 63(4): 349–350.
PMCID: PMC1811230

Technique and significance of lymphocyte transformation in allergic states.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (320K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • BENDER MA, PRESCOTT DM. DNA synthesis and mitosis in cultures of human peripheral leukocytes. Exp Cell Res. 1962 Aug;27:221–229. [PubMed]
  • Bergman B, Börjeson J, Löw B, Nordén A. Substitution of plasma in culture medium with dextran, glucose or albumin for in vitro studies of lymphocytes. Scand J Haematol. 1967;4(3):176–180. [PubMed]
  • Chalmers DG, Cooper EH, Coulson AS, Inman DR, Topping NE. Immunologically stimulated human peripheral blood lymphocytes in vitro. I. Morphological changes. Int Arch Allergy Appl Immunol. 1966;30(1):83–96. [PubMed]
  • Coulson AS, Chalmers DG. Quantitation of peripheral blood lymphocyte cultures. Nature. 1966 Jan 22;209(5021):378–381. [PubMed]
  • Halpern B, Amache N. Diagnosis of drug allergy in vitro with the lymphocyte transformation test. J Allergy. 1967 Sep;40(3):168–181. [PubMed]
  • Han T, Chawla PL, Sokal JE. Sulfapyridine-induced serum-sickness-like syndrome associated with plasmacytosis, lymphocytosis and multiclonal gamma-globulinopathy. N Engl J Med. 1969 Mar 6;280(10):547–548. [PubMed]
  • Heilman DH, McFarland W. Mitogenic activity of bacterial fractions in lymphocyte cultures. I. Purified protein derivative and polysaccharides of tuberculin. J Immunol. 1966 Jun;96(6):988–991. [PubMed]
  • Hersh EM, Harris JE. Macrophage-lymphocyte interaction in the antigen-induced blastogenic response of human peripheral blood leukocytes. J Immunol. 1968 Jun;100(6):1184–1194. [PubMed]
  • Johnson GJ, Russell PS. Reaction of human lymphocytes in culture to components of the medium. Nature. 1965 Oct 23;208(5008):343–345. [PubMed]
  • Marshall WH, Roberts KB. Continuous cinematography of human lymphocytes cultured with a phytohaemagglutinin including observations on cell division and interphase. Q J Exp Physiol Cogn Med Sci. 1965 Oct;50(4):361–374. [PubMed]
  • Moorhead JF, Connolly JJ, McFarland W. Factors affecting the reactivity of human lymphocytes in vitro. I. Cell number, duration of culture and surface area. J Immunol. 1967 Aug;99(2):413–419. [PubMed]
  • NOWELL PC. Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes. Cancer Res. 1960 May;20:462–466. [PubMed]
  • Oppenheim JJ. Relationship of in vitro lymphocyte transformation to delayed hypersensitivity in guinea pigs and man. Fed Proc. 1968 Jan-Feb;27(1):21–28. [PubMed]
  • PEARMAIN G, LYCETTE RR, FITZGERALD PH. Tuberculin-induced mitosis in peripheral blood leucocytes. Lancet. 1963 Mar 23;1(7282):637–638. [PubMed]
  • ROBBINS JH. TISSUE CULTURE STUDIES OF THE HUMAN LYMPHOCYTE. Science. 1964 Dec 25;146(3652):1648–1654. [PubMed]
  • Schellekens PT, Eijsvoogel VP. Lymphocyte transformation in vitro. I. Tissue culture conditions and quantitative measurements. Clin Exp Immunol. 1968 Jul;3(6):571–584. [PubMed]
  • Stewart CC, Ingram M. A method for counting phytohemagglutinin-stimulated lymphocytes. Blood. 1967 Apr;29(4 Suppl):628–639. [PubMed]
  • Clarke CA. Prevention of rhesus iso-immunisation. Lancet. 1968 Jul 6;2(7558):1–7. [PubMed]
  • Zeitz SJ, Van Arsdel PP, Jr, McClure DK. Specific response of human lymphocytes to pollen antigen in tissue culture. J Allergy. 1966 Dec;38(6):321–329. [PubMed]

Articles from Proceedings of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press