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Br Med J. 1972 May 20; 2(5811): 436–438.
PMCID: PMC1788022

Heparin in the Prevention of Deep Vein Thrombosis after Myocardial Infarction


A trial of continuous intravenous heparin in the prevention of deep vein thrombosis was undertaken in 48 patients who had suffered a myocardial infarction. Of the 24 control patients who did not receive heparin seven (29%) developed calf vein thrombosis as detected by the radioactive fibrinogen technique. None of the 24 heparinized patients had any evidence of venous thrombosis. This difference is significant at the 1% level.

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