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Logo of annrheumdAnnals of the Rheumatic DiseasesCurrent TOCInstructions for authors
Ann Rheum Dis. Jan 1999; 58(1): 15–19.
PMCID: PMC1752761
Effectiveness of home exercise on pain and disability from osteoarthritis of the knee: a randomised controlled trial
S. O'Reilly, K. Muir, and M. Doherty
Rheumatology Unit, City Hospital, Nottingham.
OBJECTIVE—To assess the effect of a home based exercise programme, designed to improve quadriceps strength, on knee pain and disability.
Methods—191 men and women with knee pain aged 40-80 were recruited from the community and randomised to exercise (n=113) or no intervention (n=78). The exercise group performed strengthening exercises daily for six months. The primary outcome measure was change in knee pain (Western Ontario McMaster Osteoarthritis index (WOMAC)). Secondary measures included visual analogue scales (VAS) for pain on stairs and walking and WOMAC physical function scores.
Results—WOMAC pain score reduced by 22.5% in the exercise group and by 6.2% in the control group (between group difference p<0.05, unpaired t test).VAS scores for pain also reduced in the exercise group compared with the control group (p<0.05). Physical function scores reduced by 17.4% in the exercise group and were unchanged in controls (p<0.05).
Conclusion—A simple programme of home quadriceps exercises can significantly improve self reported knee pain and function.

Keywords: knee osteoarthritis; knee pain; quadriceps strength; exercise
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Figures and Tables
Figure 1
Figure 1  
Summary data for study recruitment and completion.
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