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Infect Immun. Nov 1995; 63(11): 4553–4556.
PMCID: PMC173653
Bartonella henselae and Bartonella quintana adherence to and entry into cultured human epithelial cells.
H J Batterman, J A Peek, J S Loutit, S Falkow, and L S Tompkins
Department of Medicine, Stanford University, California 94305, USA.
Bartonella henselae expresses pili phenotypically similar to type 4 pili. B. henselae pilus expression undergoes phase variation with multiple passages. Low-passage-number, piliated B. henselae adhered to and invaded HEp-2 cells to a greater extent than did multiply passaged B. henselae with reduced pilus expression. Pili may be a pathogenic determinant for Bartonella species.
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