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Logo of archdischArchives of Disease in ChildhoodInstructions for authorsCurrent TOC
Arch Dis Child. Mar 2001; 84(3): 227–229.
PMCID: PMC1718684
Idiopathic thrombocytopenic purpura and MMR vaccine
E Miller, P Waight, C Farrington, N Andrews, J Stowe, and B Taylor
Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, Colindale, London NW9 5EQ, UK. e.miller/at/
A CAUSAL ASSOCIATION BETWEEN MEASLES—mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.

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