PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of archdischArchives of Disease in ChildhoodVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
 
Arch Dis Child. Nov 2000; 83(5): 408–412.
PMCID: PMC1718544
Community acquired pneumonia—a prospective UK study
P Drummond, J Clark, J Wheeler, A Galloway, R Freeman, and A Cant
Department of Paediatrics, Newcastle General Hospital, Westgate Road, Newcastle-upon-Tyne, UK. paula/at/medmail.com
Abstract
BACKGROUND—There are few data on paediatric community acquired pneumonia (PCAP) in the UK.
AIMS—To investigate the aetiology and most useful diagnostic tests for PCAP in the north east of England.
METHODS—A prospective study of hospital admissions with a diagnosis of PCAP.
RESULTS—A pathogen was isolated from 60% (81/136) of cases, and considered a definite or probable cause of their pneumonia in 51% (70/136). Fifty (37%) had a virus implicated (65% respiratory syncytial virus) and 19 (14%) a bacterium (7% group A streptococcus, 4% Streptococcus pneumoniae), with one mixed infection. Of a subgroup (51 patients) in whom serum antipneumolysin antibody testing was performed, 6% had evidence of pneumococcal infection, and all were under 2 years old. The best diagnostic yield was from paired serology (34%, 31/87), followed by viral immunofluorescence (33%, 32/98).
CONCLUSION—Viral infection accounted for 71% of the cases diagnosed. Group A streptococcus was the most common bacterial infective agent, with a low incidence of both Mycoplasma pneumoniae and S pneumoniae. Pneumococcal pneumonia was the most common bacterial cause of pneumonia in children under 2 years but not in older children. Inflammatory markers and chest x ray features did not differentiate viral from bacterial pneumonia; serology and viral immunofluorescence were the most useful diagnostic tests.

Articles from Archives of Disease in Childhood are provided here courtesy of
BMJ Group