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Antimicrob Agents Chemother. Mar 1990; 34(3): 489–490.
PMCID: PMC171624
Hemodialysis clearance of intravenously administered ribavirin.
T H Kramer, G G Gaar, C G Ray, L Minnich, J G Copeland, and J D Connor
Department of Pharmacology, University of Arizona Health Sciences Center, Tucson 85724.
A patient with an implanted artificial heart, acute, anuric renal failure, and disseminated influenza virus type A infection received intravenous ribavirin. Drug elimination by hemodialysis was measured. Plasma dialysis clearance averaged 93.9 +/- 8.6 ml/min. The maximum amount of ribavirin removed from the body during one period of hemodialysis was 79.1 mg. Ribavirin is not removed in important quantities by hemodialysis.
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