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Appl Environ Microbiol. May 1995; 61(5): 2040–2042.
PMCID: PMC167473
Role of C-terminal direct repeating units of the Streptococcus mutans glucosyltransferase-S in glucan binding.
M Lis, T Shiroza, and H K Kuramitsu
Department of Oral Biology, State University of New York, Buffalo 14214, USA.
The C-terminal glucan-binding domain of the glucosyltransferase-S of Streptococcus mutans GS-5 contains five 65-amino-acid direct repeating units. A series of deletion derivatives of both the glucosyltransferase-S and its glucan-binding domain were constructed and analyzed. The results demonstrated that the four C-terminal direct repeating units constituted part of the minimum domain required for glucan binding.
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