PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of bmjLink to Publisher's site
 
BMJ. 1991 May 25; 302(6787): 1235–1237.
PMCID: PMC1669912

Birth weight, current body weight, and blood pressure in late adolescence.

Abstract

Objective--To study the effect of birth weight and body weight on blood pressure in late adolescence. Design--Analysis of data on weight, height, and blood pressure at age 17 of subjects from the Jerusalem perinatal study, according to their birth weight. Data for men and women were analysed separately. Setting--Jerusalem, Israel. Subjects--32,580 subjects (19,734 men and 12,846 women) born in the three major hospitals in Jerusalem during 1964-71 and subsequently drafted in to the army. MAIN OUTCOME MEASURES--Correlations between birth weight and blood pressure at age 17 and weight and height at age 17 and blood pressure. Results--Diastolic and systolic blood pressures were associated with birth weight in both young men and young women, but the correlation coefficients were low. A high body weight at age 17 (greater than 66 kg for women, greater than 75 kg for men) rather than a low birth weight (less than 2500 g) was linked with higher systolic and diastolic blood pressures in both men and women (p less than 0.01). Conclusions--Intrauterine environment, as reflected by birth weight, has little effect on blood pressure in young men and women. Modification of factors which lead to excess weight during adolescence may have a major role in preventing hypertension in adults.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (655K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Barker DJ, Winter PD, Osmond C, Margetts B, Simmonds SJ. Weight in infancy and death from ischaemic heart disease. Lancet. 1989 Sep 9;2(8663):577–580. [PubMed]
  • Barker DJ, Osmond C, Law CM. The intrauterine and early postnatal origins of cardiovascular disease and chronic bronchitis. J Epidemiol Community Health. 1989 Sep;43(3):237–240. [PMC free article] [PubMed]
  • Ounsted MK, Cockburn JM, Moar VA, Redman CW. Factors associated with the blood pressures of children born to women who were hypertensive during pregnancy. Arch Dis Child. 1985 Jul;60(7):631–635. [PMC free article] [PubMed]
  • Gennser G, Rymark P, Isberg PE. Low birth weight and risk of high blood pressure in adulthood. Br Med J (Clin Res Ed) 1988 May 28;296(6635):1498–1500. [PMC free article] [PubMed]
  • Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ. 1989 Mar 4;298(6673):564–567. [PMC free article] [PubMed]
  • Barker DJ, Bull AR, Osmond C, Simmonds SJ. Fetal and placental size and risk of hypertension in adult life. BMJ. 1990 Aug 4;301(6746):259–262. [PMC free article] [PubMed]
  • Higgins M, Keller J, Moore F, Ostrander L, Metzner H, Stock L. Studies of blood pressure in Tecumseh, Michigan. I. Blood pressure in young people and its relationship to personal and familial characteristics and complications of pregnancy in mothers. Am J Epidemiol. 1980 Feb;111(2):142–155. [PubMed]
  • Harlap S, Davies AM, Grover NB, Prywes R. The Jerusalem perinatal study: the first decade 1964--73. Isr J Med Sci. 1977 Nov;13(11):1073–1091. [PubMed]
  • Kark JD, Kedem R, Revach M. Medical examination of Israeli 17-year-olds before military service as a national resource for health information. Isr J Med Sci. 1986 Mar-Apr;22(3-4):318–325. [PubMed]
  • Wilson SL, Gaffney FA, Laird WP, Fixler DE. Body size, composition, and fitness in adolescents with elevated blood pressures. Hypertension. 1985 May-Jun;7(3 Pt 1):417–422. [PubMed]
  • Lauer RM, Clarke WR. Childhood risk factors for high adult blood pressure: the Muscatine Study. Pediatrics. 1989 Oct;84(4):633–641. [PubMed]
  • Elford J, Phillips A, Thomson AG, Shaper AG. Migration and geographic variations in blood pressure in Britain. BMJ. 1990 Feb 3;300(6720):291–295. [PMC free article] [PubMed]

Articles from BMJ : British Medical Journal are provided here courtesy of BMJ Group