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Skull base surgery. 1998; 8(4): 237–241.
PMCID: PMC1656708

Extra-Abdominal Fibromatosis (Desmoid Tumor) Arising in the Infratemporal Fossa

A Case Report


Aggressive fibromatosis (or desmoid tumor) refers to a histologically benign but locally aggressive lesion arising from musculoaponeurotic structures in various anatomic sites. Extra-abdominal desmoids represent about one third of all desmoid tumors; of these only about 11 to 15% arise in the head and neck. Desmoid tumors arising in the infratemporal fossa are exceedingly rare; to our knowledge only one such tumor has been reported in the literature. We present a desmoid tumor arising in the infratemporal fossa with intracranial extension in a twenty-seven year old male and review the literature on this rare condition.

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Selected References

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  • Fasching MC, Saleh J, Woods JE. Desmoid tumors of the head and neck. Am J Surg. 1988 Oct;156(4):327–331. [PubMed]
  • Fowler CB, Hartman KS, Brannon RB. Fibromatosis of the oral and paraoral region. Oral Surg Oral Med Oral Pathol. 1994 Apr;77(4):373–386. [PubMed]
  • O'Ryan F, Eversole LR, Alikpala A. Juvenile fibromatosis of the infratemporal fossa. Oral Surg Oral Med Oral Pathol. 1987 Nov;64(5):603–608. [PubMed]
  • Reitamo JJ, Häyry P, Nykyri E, Saxén E. The desmoid tumor. I. Incidence, sex-, age- and anatomical distribution in the Finnish population. Am J Clin Pathol. 1982 Jun;77(6):665–673. [PubMed]
  • Masson JK, Soule EH. Desmoid tumors of the head and neck. Am J Surg. 1966 Oct;112(4):615–622. [PubMed]
  • Häyry P, Reitamo JJ, Tötterman S, Hopfner-Hallikainen D, Sivula A. The desmoid tumor. II. Analysis of factors possibly contributing to the etiology and growth behavior. Am J Clin Pathol. 1982 Jun;77(6):674–680. [PubMed]
  • Lim CL, Walker MJ, Mehta RR, Das Gupta TK. Estrogen and antiestrogen binding sites in desmoid tumors. Eur J Cancer Clin Oncol. 1986 May;22(5):583–587. [PubMed]
  • GARDNER EJ. Follow-up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas and epidermal cysts. Am J Hum Genet. 1962 Dec;14:376–390. [PubMed]
  • Batsakis JG, Raslan W. Extra-abdominal desmoid fibromatosis. Ann Otol Rhinol Laryngol. 1994 Apr;103(4 Pt 1):331–334. [PubMed]
  • Anthony T, Rodriguez-Bigas MA, Weber TK, Petrelli NJ. Desmoid tumors. J Am Coll Surg. 1996 Apr;182(4):369–377. [PubMed]
  • Winer-Muram HT, Bowman LC, Parham D. Intrathoracic desmoid tumor: CT and MRI appearance. South Med J. 1994 Oct;87(10):1007–1009. [PubMed]
  • McKinnon JG, Neifeld JP, Kay S, Parker GA, Foster WC, Lawrence W., Jr Management of desmoid tumors. Surg Gynecol Obstet. 1989 Aug;169(2):104–106. [PubMed]
  • Posner MC, Shiu MH, Newsome JL, Hajdu SI, Gaynor JJ, Brennan MF. The desmoid tumor. Not a benign disease. Arch Surg. 1989 Feb;124(2):191–196. [PubMed]
  • Reitamo JJ. The desmoid tumor. IV. Choice of treatment, results, and complications. Arch Surg. 1983 Nov;118(11):1318–1322. [PubMed]
  • Miralbell R, Suit HD, Mankin HJ, Zuckerberg LR, Stracher MA, Rosenberg AE. Fibromatoses: from postsurgical surveillance to combined surgery and radiation therapy. Int J Radiat Oncol Biol Phys. 1990 Mar;18(3):535–540. [PubMed]
  • Sherman NE, Romsdahl M, Evans H, Zagars G, Oswald MJ. Desmoid tumors: a 20-year radiotherapy experience. Int J Radiat Oncol Biol Phys. 1990 Jul;19(1):37–40. [PubMed]
  • Leibel SA, Wara WM, Hill DR, Bovill EG, Jr, de Lorimier AA, Beckstead JH, Phillips TL. Desmoid tumors: local control and patterns of relapse following radiation therapy. Int J Radiat Oncol Biol Phys. 1983 Aug;9(8):1167–1171. [PubMed]
  • Acker JC, Bossen EH, Halperin EC. The management of desmoid tumors. Int J Radiat Oncol Biol Phys. 1993 Aug 1;26(5):851–858. [PubMed]
  • Patel SR, Evans HL, Benjamin RS. Combination chemotherapy in adult desmoid tumors. Cancer. 1993 Dec 1;72(11):3244–3247. [PubMed]
  • Weiss AJ, Lackman RD. Low-dose chemotherapy of desmoid tumors. Cancer. 1989 Sep 15;64(6):1192–1194. [PubMed]
  • Seiter K, Kemeny N. Successful treatment of a desmoid tumor with doxorubicin. Cancer. 1993 Apr 1;71(7):2242–2244. [PubMed]
  • Goepfert H, Cangir A, Ayala AG, Eftekhari F. Chemotherapy of locally aggressive head and neck tumors in the pediatric age group. Desmoid fibromatosis and nasopharyngeal angiofibroma. Am J Surg. 1982 Oct;144(4):437–444. [PubMed]
  • Wilcken N, Tattersall MH. Endocrine therapy for desmoid tumors. Cancer. 1991 Sep 15;68(6):1384–1388. [PubMed]
  • Sportiello DJ, Hoogerland DL. A recurrent pelvic desmoid tumor successfully treated with tamoxifen. Cancer. 1991 Mar 1;67(5):1443–1446. [PubMed]
  • Bauernhofer T, Stöger H, Schmid M, Smola M, Gürtl-Lackner B, Höfler G, Ranner G, Reisinger E, Samonigg H. Sequential treatment of recurrent mesenteric desmoid tumor. Cancer. 1996 Mar 15;77(6):1061–1065. [PubMed]
  • Klein WA, Miller HH, Anderson M, DeCosse JJ. The use of indomethacin, sulindac, and tamoxifen for the treatment of desmoid tumors associated with familial polyposis. Cancer. 1987 Dec 15;60(12):2863–2868. [PubMed]
  • Waddell WR, Gerner RE, Reich MP. Nonsteroid antiinflammatory drugs and tamoxifen for desmoid tumors and carcinoma of the stomach. J Surg Oncol. 1983 Mar;22(3):197–211. [PubMed]

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