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Skull base surgery. 1998; 8(2): 93–97.
PMCID: PMC1656693

Giant Cell Tumor of the Sphenoid Bone*


Objective and Importance: Giant cell tumor of the sphenoid bone is extremely unusual. This tumor is usually located in long bones and is rarely located in the cranial vault. It must be differentiated from reparative granuloma and the Brown tumor of hyperparathyroidism. This case report is only the second involving a patient in the first decade.

Clinical Presentation: A 9-year-old girl presented with cephalgia and diplopia. Radiographic imaging revealed an erosive mass in the clivus.

Intervention: The patient underwent an extended transphenoidal resection of the clivus. This was followed with 57.6 CGE in 32 fractionated doses.

Conclusion: At 1 year follow-up, the tumor remains stable. Based on anecdotal evidence, attempted resection with adjuvant radiation therapy allows for long-term survival in these patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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