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Skull base surgery. 1991 July; 1(3): 165–167.
PMCID: PMC1656288

Natural History of Acoustic Neuromas


The growth rate of acoustic neuromas was studied in a series of 50 patients who underwent follow-up imaging studies, since surgery was not performed after the initial diagnostic study or only performed after the follow-up studies. In 50% of the cases the tumor did not grow during the length of the follow-up. In the other patients the growth was less than 50% of the original tumor size in all but four. No correlation was observed between tumor growth, length of the follow-up, and age of the patient. Our results suggest a change in the management of this benign tumor.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Tos M, Thomsen J. Epidemiology of acoustic neuromas. J Laryngol Otol. 1984 Jul;98(7):685–692. [PubMed]
  • Wazen J, Silverstein H, Norrell H, Besse B. Preoperative and postoperative growth rates in acoustic neuromas documented with CT scanning. Otolaryngol Head Neck Surg. 1985 Apr;93(2):151–155. [PubMed]
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  • Thomsen J, Tos M. Acoustic neuromas. Diagnostic delay, growth rate and possible non-surgical treatment. Acta Otolaryngol Suppl. 1988;452:26–33. [PubMed]
  • Lesser TH, Janzer RC, Kleihues P, Fisch U. Clinical growth rate of acoustic schwannomas: correlation with the growth fraction as defined by the monoclonal antibody ki-67. Skull Base Surg. 1991;1(1):11–15. [PMC free article] [PubMed]
  • Welling DB, Glasscock ME, 3rd, Woods CI, Jackson CG. Acoustic neuroma: a cost-effective approach. Otolaryngol Head Neck Surg. 1990 Sep;103(3):364–370. [PubMed]

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