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Skull Base. 2002 February; 12(1): 19–26.
PMCID: PMC1654773

Meningiomas of the Internal Auditory Canal

Two Case Reports

Abstract

Meningiomas represent 3 to 12% of the tumors that involve the cerebellopontine angle and internal auditory canal (IAC). Intracanalicular meningiomas, however, are rare. Only 10 well-documented cases have been reported in the English literature. The differential diagnosis includes acoustic neuromas, facial nerve neuromas, hemangiomas, lipomas, and meningiomas. We report two new cases of intracanalicular meningioma. Both patients had unilateral tinnitus. In case 1, the patient also experienced sensorineural hearing loss with unilateral tinnitus. In case 1, the lesion appeared hyperintense on T1-weighted and hypointense on T2-weighted magnetic resonance images. In case 2, the patient had an enhancing lesion in the right IAC. The tumors were moderately cellular, and meningeal whorls and meningothelial inclusions were present. Immunohistochemical staining revealed the tumors to be positive for epithelial membrane antigen (EMA) and negative for S-100 protein. The radiologic findings that help distinguish a meningioma from other lesions are reviewed.

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Selected References

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  • Kohan D, Downey LL, Lim J, Cohen NL, Elowitz E. Uncommon lesions presenting as tumors of the internal auditory canal and cerebellopontine angle. Am J Otol. 1997 May;18(3):386–392. [PubMed]
  • Nedzelski J, Tator C. Other cerebellopontine angle (non-acoustic neuroma) tumors. J Otolaryngol. 1982 Aug;11(4):248–252. [PubMed]
  • Bohrer PS, Chole RA. Unusual lesions of the internal auditory canal. Am J Otol. 1996 Jan;17(1):143–149. [PubMed]
  • Caylan R, Falcioni M, De Donato G, Ferrara S, Russo A, Taibah A, Sanna M. Intracanalicular meningiomas. Otolaryngol Head Neck Surg. 2000 Jan;122(1):147–150. [PubMed]
  • Baguley DM, Beynon GJ, Grey PL, Hardy DG, Moffat DA. Audio-vestibular findings in meningioma of the cerebello-pontine angle: a retrospective review. J Laryngol Otol. 1997 Nov;111(11):1022–1026. [PubMed]
  • Brackmann DE, Bartels LJ. Rare tumors of the cerebellopontine angle. Otolaryngol Head Neck Surg (1979) 1980 Sep-Oct;88(5):555–559. [PubMed]
  • Moffat DA, Saunders JE, McElveen JT, Jr, McFerran DJ, Hardy DG. Unusual cerebello-pontine angle tumours. J Laryngol Otol. 1993 Dec;107(12):1087–1098. [PubMed]
  • Thomsen J. Cerebellopontine angle tumours, other than acoustic neuromas. A report on 34 cases. A presentation of 7 bilateral acoustic neuromas. Acta Otolaryngol. 1976 Jul-Aug;82(1-2):106–111. [PubMed]
  • Zeitouni AG, Zagzag D, Cohen NL. Meningioma of the internal auditory canal. Ann Otol Rhinol Laryngol. 1997 Aug;106(8):657–661. [PubMed]
  • Langman AW, Jackler RK, Althaus SR. Meningioma of the internal auditory canal. Am J Otol. 1990 May;11(3):201–204. [PubMed]
  • Singh KP, Smyth GD, Allen IV. Intracanalicular meningioma. J Laryngol Otol. 1975 May;89(5):549–552. [PubMed]
  • Brookler KH, Hoffman RA, Camins M, Terzakis J. Trilobed meningioma: ampulla of posterior semicircular canal, internal auditory canal, and cerebellopontine angle. Am J Otol. 1980 Jan;1(3):171–173. [PubMed]
  • Dinh DH, Clark SB, Whitehead M, Amedee R, Bhattacharjee MB. Intracanalicular meningioma. South Med J. 2000 Jun;93(6):618–621. [PubMed]
  • Martinez Devesa PM, Wareing MJ, Moffat DA. Meningioma in the internal auditory canal. J Laryngol Otol. 2001 Jan;115(1):48–49. [PubMed]
  • Collins VP, Nordenskjöld M, Dumanski JP. The molecular genetics of meningiomas. Brain Pathol. 1990 Sep;1(1):19–24. [PubMed]
  • Ruttledge MH, Sarrazin J, Rangaratnam S, Phelan CM, Twist E, Merel P, Delattre O, Thomas G, Nordenskjöld M, Collins VP, et al. Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas. Nat Genet. 1994 Feb;6(2):180–184. [PubMed]
  • Adegbite AB, Khan MI, Paine KW, Tan LK. The recurrence of intracranial meningiomas after surgical treatment. J Neurosurg. 1983 Jan;58(1):51–56. [PubMed]
  • Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL. Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg. 1985 Jan;62(1):18–24. [PubMed]
  • El-Kashlan HK, Zeitoun H, Arts HA, Hoff JT, Telian SA. Recurrence of acoustic neuroma after incomplete resection. Am J Otol. 2000 May;21(3):389–392. [PubMed]
  • Shelton C. Unilateral acoustic tumors: how often do they recur after translabyrinthine removal? Laryngoscope. 1995 Sep;105(9 Pt 1):958–966. [PubMed]
  • Tatagiba M, Samii M, Matthies C, el Azm M, Schönmayr R. The significance for postoperative hearing of preserving the labyrinth in acoustic neurinoma surgery. J Neurosurg. 1992 Nov;77(5):677–684. [PubMed]
  • Thomassin JM, Pellet W, Epron JP, Braccini F, Roche PH. Les récidives des neurinomes de l'acoustique après exérèse chirurgicale. Ann Otolaryngol Chir Cervicofac. 2001 Feb;118(1):3–10. [PubMed]
  • Guerin C, Sampath P, Long DM. Acoustic neuroma: outcome of surgical resection and study on the anatomy of facial and cochlear nerves. Ann Acad Med Singapore. 1999 May;28(3):402–408. [PubMed]
  • Driscoll CL, Jackler RK, Pitts LH, Brackmann DE. Lesions of the internal auditory canal and cerebellopontine angle in an only hearing ear: is surgery ever advisable? Am J Otol. 2000 Jul;21(4):573–581. [PubMed]
  • Sekhar LN, Gormley WB, Wright DC. The best treatment for vestibular schwannoma (acoustic neuroma): microsurgery or radiosurgery? Am J Otol. 1996 Jul;17(4):676–689. [PubMed]
  • Singh VP, Kansai S, Vaishya S, Julka PK, Mehta VS. Early complications following gamma knife radiosurgery for intracranial meningiomas. J Neurosurg. 2000 Dec;93 (Suppl 3):57–61. [PubMed]
  • Suh JH, Barnett GH, Sohn JW, Kupelian PA, Cohen BH. Results of linear accelerator-based stereotactic radiosurgery for recurrent and newly diagnosed acoustic neuromas. Int J Cancer. 2000 Jun 20;90(3):145–151. [PubMed]

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