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Logo of arthrestherBioMed Centralbiomed central web sitesearchsubmit a manuscriptregisterthis articleArthritis Research & Therapy
 
Arthritis Res Ther. 2003; 5(2): 51–53.
Published online Jan 13, 2003.
PMCID: PMC165031
New hope for haplotype mapping
John I Bellcorresponding author1
1John Radcliffe Hospital, Oxford, UK
corresponding authorCorresponding author.
John I Bell: Regius/at/medsci.ox.ac.uk
Received November 1, 2002; Accepted November 20, 2002.
Abstract
The systematic analysis of polymorphisms across large parts of the human genome has begun to provide the first information on haplotypes and the problem of linkage disequilibrium across large genomic regions. These data suggest that significant regions of the genome show highly conserved haplotypes, potentially enhancing the ability to detect disease associations.
Keywords: evolution, genetics, haplotypes, human leukocyte antigen
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