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(A) and (B) Example of traces of outward sIPSCs recorded from a pup (A) and adult (B) DGC. Dashed box on each top trace denotes expanded segment on the bottom. Scales indicate 0.5 s/50 ms (top/bottom), 10 pA.
(C) and (D) Two-dimensional histograms of rise and decay time of individual sIPSCs recorded from pup ([C] n = 695 events) and adult DGCs ([D] n = 1,160 events). Color scale indicates the relative frequency for each bin.
(E) Cumulative histograms of rise and decay time of all sIPSCs recorded from pup (green) and adult DGCs (red). Same data as shown in (C) and (D).
(F) Frequency of sIPSCs (pup, n = 10 neurons; adult, n = 16; p = 0.94; t-test).
(G) Peak amplitude of sIPSCs (pup, n = 10; adult, n = 14; p = 0.44).
(H) Kinetics of sIPSCs. Inset: scaled averages of sIPSCs (pup, green; adult, red). Scale bar indicates 50 ms. All experiments conducted in the presence of kyn at Vhold = 0 mV with an internal solution containing high [Cl−]. (n, same as in [F]; rise time, p = 0.37; decay time, p = 0.41).