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Arch Dis Child. 1983 July; 58(7): 539–541.
PMCID: PMC1628177

Lithium toxicity in a neonate.


Severe transplacental lithium toxicity in a neonate is described. There were gross functional lesions of the cardiovascular, renal, and neuromuscular systems with no structural abnormalities. At 1 year of age cardiovascular and renal function is normal, but there is developmental delay.

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Selected References

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  • Singer I, Rotenberg D. Mechanisms of lithium action. N Engl J Med. 1973 Aug 2;289(5):254–260. [PubMed]
  • Schou M, Goldfield MD, Weinstein MR, Villeneuve A. Lithium and pregnancy. I. Report from the Register of Lithium Babies. Br Med J. 1973 Apr 21;2(5859):135–136. [PMC free article] [PubMed]
  • Von Hartitzsch B, Hoenich NA, Leigh RJ, Wilkinson R, Frost TH, Weddel A, Posen GA. Permanent neurological sequelae despite haemodialysis for lithium intoxication. Br Med J. 1972 Dec 30;4(5843):757–759. [PMC free article] [PubMed]

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