Molecular characterization of the OXA-7 beta-lactamase gene.

Antimicrob Agents Chemother. 1995 June; 39(6): 1379–1382.

PMCID: PMC162747

Molecular characterization of the OXA-7 beta-lactamase gene.

E Scoulica, A Aransay, and Y Tselentis

Department of Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete, Heraklion-Crete, Greece.

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Abstract

The OXA-7 gene, which encodes an oxacillinase, was cloned from plasmid pMG202 of Escherichia coli isolate 7181 (A. A. Medeiros, M. Cohenford, and G. A. Jacoby, Antimicrob. Agents Chemother. 27:715-719, 1985) and sequenced. The nucleotide sequence of the OXA-7 gene was closely related to that of the OXA-10 (PSE-2) gene, with a derived amino acid sequence of the OXA-7 enzyme showing greater than 95% homology with those of OXA-10 and OXA-11.

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