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Br Med J. 1973 April 21; 2(5859): 137–138.
PMCID: PMC1589270

Lithium and Pregnancy—II, Hazards to Women Given Lithium During Pregnancy and Delivery


The renal lithium clearance of a manic-depressive woman rose when she became pregnant and fell to the prepregnancy level when she gave birth. The lithium clearances of four healthy women were higher during pregnancy than after delivery. This emphasizes the need for frequent determinations of the serum lithium concentration and appropriate dosage adjustments during pregnancy and delivery.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Aoki FY, Ruedy JR. Lithium intoxication. Can Med Assoc J. 1972 Jan 22;106(2):112–112. [PMC free article] [PubMed]
  • Schou M, Baastrup PC, Grof P, Weis P, Angst J. Pharmacological and clinical problems of lithium prophylaxis. Br J Psychiatry. 1970 Jun;116(535):615–619. [PubMed]
  • Vacaflor L, Lehmann HE, Ban TA. Side effects and teratogenicity of lithium carbonate treatment. J Clin Pharmacol J New Drugs. 1970 Nov-Dec;10(6):387–389. [PubMed]
  • Weinstein MR, Goldfield MD, Wilbanks GD. Lithium ion toxicity and pregnancy. JAMA. 1970 Nov 16;214(7):1325–1326. [PubMed]
  • Wilbanks GD, Bressler B, Peete CH, Jr, Cherny WB, London WL. Toxic effects of lithium carbonate in a mother and newborn infant. JAMA. 1970 Aug 3;213(5):865–867. [PubMed]
  • Woody JN, London WL, Wilbanks GD., Jr Lithium toxicity in a newborn. Pediatrics. 1971 Jan;47(1):94–96. [PubMed]

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