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Br Med J (Clin Res Ed). 1983 January 22; 286(6361): 251–252.
PMCID: PMC1546453

Acute acalculous cholecystitis complicating systemic lupus erythematosus: case report and review.


A case of acalculous cholecystitis presented as an acute abdominal emergency in a 22 year old woman with severe systemic lupus erythematosus. At the time of presentation the patient was receiving high doses of prednisone and cyclophosphamide to control her underlying disease. Histological examination of the biopsy specimen from the gall bladder showed lupus vasculitis. This complication of systemic lupus erythematosus has not been reported before. Laboratory studies and changes in lupus activity may fail to predict the onset of cholecystitis.

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Selected References

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  • Stoddard CJ, Kay PH, Simms JM, Kennedy A, Hughes P. Acute abdominal complications of systemic lupus erythematosus. Br J Surg. 1978 Sep;65(9):625–628. [PubMed]
  • Hoffman BI, Katz WA. The gastrointestinal manifestations of systemic lupus erythematosus: a review of the literature. Semin Arthritis Rheum. 1980 May;9(4):237–247. [PubMed]
  • POLLAK VE, GROVE WJ, KARK RM, MUEHRCKE RC, PIRANI CL, STECK IE. Systemic lupus erythematosus simulating acute surgical condition of the abdomen. N Engl J Med. 1958 Aug 7;259(6):258–266. [PubMed]
  • Lasser A, Ghofrany S. Necrotizing granulomatous vasculitis (allergic granulomatosis) of the gallbladder. Gastroenterology. 1976 Oct;71(4):660–662. [PubMed]

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