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Arch Dis Child. 1978 September; 53(9): 704–706.
PMCID: PMC1545107

Treatment of acute viral croup.


Total respiratory resistance (RT) was measured before and after nebulised alpha-adrenergic stimulant therapy in 8 children aged 4 to 18 months who had the clinical symptoms of acute viral croup. In 7 children there was a mean fall in RT of 30% after treatment, associated with an improvement in their clinical condition. This improvement was shortlived, the resistance returning to pretreatment levels within 30 minutes. The remaining child showed no improvement after phenylephrine but was subsequently found to have acute epiglottitis. Nebulised water did not produce any change, indicating that the response was not due to moisture alone.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Cogswell JJ. Forced oscillation technique for determination of resistance to breathing in children. Arch Dis Child. 1973 Apr;48(4):259–266. [PMC free article] [PubMed]
  • Gardner HG, Powell KR, Roden VJ, Cherry JD. The evaluation of racemic epinephrine in the treatment of infectious croup. Pediatrics. 1973 Jul;52(1):52–55. [PubMed]
  • Lenney W, Milner AD. Recurrent wheezing in the preschool child. Arch Dis Child. 1978 Jun;53(6):468–473. [PMC free article] [PubMed]
  • Lenney W, Milner AD. At what age do bronchodilator drugs work? Arch Dis Child. 1978 Jul;53(7):532–535. [PMC free article] [PubMed]
  • Taussig LM, Castro O, Beaudry PH, Fox WW, Bureau M. Treatment of laryngotracheobronchitis (croup). Use of intermittent positive-pressure breathing and racemic epinephrine. Am J Dis Child. 1975 Jul;129(7):790–793. [PubMed]

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