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Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
Proc R Soc Med. 1977; 70(Suppl 3): 65–72.
PMCID: PMC1543564

Mechanism of inhibition of collagen crosslinking by penicillamine.

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Selected References

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  • Deshmukh A, Deshmukh K, Nimni ME. Synthesis of aldehydes and their interactions during the in vitro aging of collagen. Biochemistry. 1971 Jun 8;10(12):2337–2342. [PubMed]
  • Deshmukh K, Nimni M. Soluble collagen with high aldehyde content extracted from insoluble collagen with mercaptoethylamine. Biochim Biophys Acta. 1968 Jan 22;154(1):258–260. [PubMed]
  • GROSS J. An intermolecular defect of collagen in experimental lathyrism. Biochim Biophys Acta. 1963 Apr 2;71:250–252. [PubMed]
  • Harris ED, Jr, Sjoerdsma A. Effect of penicillamine on human collagen and its possible application to treatment of scleroderma. Lancet. 1966 Nov 5;2(7471):996–999. [PubMed]
  • Klein L. Reversible transformation of fibrous collagen to a soluble state in vivo. Proc Natl Acad Sci U S A. 1969 Mar;62(3):920–927. [PubMed]
  • Klein L, Nowacek CJ. Effect of penicillamine on new and pre-existing (3H) collagen in vivo. Biochim Biophys Acta. 1969 Dec 23;194(2):504–512. [PubMed]
  • LEVENE CI, GROSS J. Alterations in state of molecular aggregation of collagen induced in chick embryos by beta-aminopropionitrile (lathyrus factor). J Exp Med. 1959 Nov 1;110:771–790. [PMC free article] [PubMed]
  • Nimni ME, Deshmukh K, Bavetta LA. Turnover and age distribution of a collagen fraction extractable from rat skin by mercaptoethylamine. Arch Biochem Biophys. 1967 Nov;122(2):292–298. [PubMed]
  • Nimni ME, Deshmukh K, Gerth N. Collagen defect induced by penicillamine. Nat New Biol. 1972 Dec 13;240(102):220–221. [PubMed]
  • Nimni ME, Deshmukh K, Gerth N, Bavetta LA. Changes in collagen metabolism associated with the administration of penicillamine and various amino and thiol compounds. Biochem Pharmacol. 1969 Apr;18(4):707–714. [PubMed]
  • Rojkind M, Júarez H. The nature of the collagen defect in lathyrism. Biochem Biophys Res Commun. 1966 Nov 22;25(4):481–486. [PubMed]
  • Siegel RC. Collagen cross-linking. Effect of D-penicillamine on cross-linking in vitro. J Biol Chem. 1977 Jan 10;252(1):254–259. [PubMed]
  • Siegel RC, Pinnell SR, Martin GR. Cross-linking of collagen and elastin. Properties of lysyl oxidase. Biochemistry. 1970 Nov 10;9(23):4486–4492. [PubMed]
  • Zika JM, Klein L. Relative and absolute changes in skin collagen mass in the rat. Biochim Biophys Acta. 1971 Feb 16;229(2):509–515. [PubMed]

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