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Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
Proc R Soc Med. 1977 December; 70(12): 845–850.
PMCID: PMC1543526

Cell differentiation and the biological significance of inappropriate tumour products.

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Selected References

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  • Andrew A. Further evidence that enterochromaffin cells are not derived from the neural crest. J Embryol Exp Morphol. 1974 Jun;31(3):589–598. [PubMed]
  • Azzopardi JG, Whittaker RS. Bronchial carcinoma and hypercalcaemia. J Clin Pathol. 1969 Nov;22(6):718–724. [PMC free article] [PubMed]
  • Azzopardi JG, Williams ED. Pathology of 'nonendocrine' tumors associated with Cushing's syndrome. Cancer. 1968 Aug;22(2):274–286. [PubMed]
  • Bensch KG, Corrin B, Pariente R, Spencer H. Oat-cell carcinoma of the lung. Its origin and relationship to bronchial carcinoid. Cancer. 1968 Dec;22(6):1163–1172. [PubMed]
  • Bloomfield GA, Holdaway IM, Corrin B, Ratcliffe JG, Rees GM, Ellison M, Rees LH. Lung tumours and ACTH production. Clin Endocrinol (Oxf) 1977 Feb;6(2):95–104. [PubMed]
  • Coombes RC, Hillyard C, Greenberg PB, MacIntyre I. Plasma-immunoreactive-calcitonin in patients with non-thyroid tumours. Lancet. 1974 Jun 1;1(7866):1080–1083. [PubMed]
  • Deftos LJ, Roos BA, Bronzert D, Parthemore JG. Immunochemical heterogeneity of calcitonin in plasma. J Clin Endocrinol Metab. 1975 Mar;40(3):409–412. [PubMed]
  • Ellison M, Woodhouse D, Hillyard C, Dowsett M, Coombes RC, Gilby ED, Greenberg PB, Neville AM. Immunoreactive calcitonin production by human lung carcinoma cells in culture. Br J Cancer. 1975 Sep;32(3):373–379. [PMC free article] [PubMed]
  • George JM, Capen CC, Phillips AS. Biosynthesis of vasopressin in vitro and ultrastructure of a bronchogenic carcinoma. Patient with the syndrome of inappropriate secretion of antidiuretic hormone. J Clin Invest. 1972 Jan;51(1):141–148. [PMC free article] [PubMed]
  • Gewirtz G, Yalow RS. Ectopic ACTH production in carcinoma of the lung. J Clin Invest. 1974 Apr;53(4):1022–1032. [PMC free article] [PubMed]
  • Greenberg PB, Martin TJ, Beck C, Burger HG. Synthesis and release of human growth hormone from lung carcinoma in cell culture. Lancet. 1972 Feb 12;1(7746):350–352. [PubMed]
  • Hadorn E. Proliferation and dynamics of cell heredity in blastema cultures of Drosophila. Natl Cancer Inst Monogr. 1969 Jul;31:351–364. [PubMed]
  • Horai R, Nishihara H, Tateishi R, Matsuda M, Hattori S. Oat-cell carcinoma of the lung simultaneously producing ACTH and serotonin. J Clin Endocrinol Metab. 1973 Aug;37(2):212–219. [PubMed]
  • Levine RJ, Metz SA. A classification of ectopic hormone-producing tumors. Ann N Y Acad Sci. 1974;230:533–546. [PubMed]
  • Lieblich JM, Weintraub BD, Krauth GH, Kohler PO, Rabson AS, Rosen SW. Ectopic and eutopic secretion of chorionic gonadotropin and its sub-nits in vitro: comparison of clonal strains from carcinomas of lung and placenta. J Natl Cancer Inst. 1976 May;56(5):911–917. [PubMed]
  • Lowry PJ, Rees LH, Tomlin S, Gillies G, Landon J. Chemical characterization of ectopic ACTH purified from a malignant thymic carcinoid tumor. J Clin Endocrinol Metab. 1976 Oct;43(4):831–835. [PubMed]
  • Melmed RN, Benitez CJ, Holt SJ. Intermediate cells of the pancreas. I. Ultrastructural characterization. J Cell Sci. 1972 Sep;11(2):449–475. [PubMed]
  • Milhaud G, Calmette C, Taboulet J, Julienne A, Moukhtar MS. Letter: Hypersecretion of calcitonin in neoplastic conditions. Lancet. 1974 Mar 16;1(7855):462–463. [PubMed]
  • Orth DN. Establishment of human malignant melanoma clonal cell lines that secrete ectopic adrenocorticotropin. Nat New Biol. 1973 Mar 7;242(114):26–28. [PubMed]
  • Pictet RL, Rall LB, Phelps P, Rutter WJ. The neural crest and the origin of the insulin-producing and other gastrointestinal hormone-producing cells. Science. 1976 Jan 16;191(4223):191–192. [PubMed]
  • Rabson AS, Rosen SW, Tashijan AH, Jr, Weintraub BD. Production of human chorionic gonadotropin in vitro by a cell line derived from a carcinoma of the lung. J Natl Cancer Inst. 1973 Mar;50(3):669–674. [PubMed]
  • Rees LH. The biosynthesis of hormones by non-endocrine tumours--a review. J Endocrinol. 1975 Oct;67(1):143–175. [PubMed]
  • Riggs BL, Arnaud CD, Reynolds JC, Smith LH. Immunologic differentiation of primary hyperparathyroidism from hyperparathyroidism due to nonparathyroid cancer. J Clin Invest. 1971 Oct;50(10):2079–2083. [PMC free article] [PubMed]
  • Scott AP, Ratcliffe JG, Rees LH, Landon J, Bennett HP, Lowry PJ, McMartin C. Pituitary peptide. Nat New Biol. 1973 Jul 18;244(133):65–67. [PubMed]
  • Silva OL, Becker KL, Primack A, Doppman JL, Snider RH. Hypercalcitonemia in bronchogenic cancer. Evidence for thyroid origin of the hormone. JAMA. 1975 Oct 13;234(2):183–185. [PubMed]
  • Singer FR, Habener JF. Multiple immunoreactive forms of calcitonin in human plasma. Biochem Biophys Res Commun. 1974 Nov 27;61(2):710–716. [PubMed]
  • Tashjian AH, Jr, Weintraub BD, Barowsky NJ, Rabson AS, Rosen SW. Subunits of human chorionic gonadotropin: unbalanced synthesis and secretion by clonal cell strains derived from a bronchogenic carcinoma. Proc Natl Acad Sci U S A. 1973 May;70(5):1419–1422. [PubMed]
  • Vaitukaitis JL. Peptide hormones as tumor markers. Cancer. 1976 Jan;37(1 Suppl):567–572. [PubMed]
  • Weintraub BD, Krauth G, Rosen SW, Babson AS. Differences between purified ectopic and normal alpha subnits of human glycoprotein hormones. J Clin Invest. 1975 Oct;56(4):1043–1052. [PMC free article] [PubMed]
  • Yalow RS, Berson SA. Characteristics of "big ACTH" in human plasma and pituitary extracts. J Clin Endocrinol Metab. 1973 Mar;36(3):415–423. [PubMed]

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