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Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
 
Proc R Soc Med. 1977; 70(Suppl 8): 7–12.
PMCID: PMC1542787

Cinnarizine in the Treatment of Peripheral Vascular Disease

Mechanisms Related to its Clinical Action

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Allewijn FT. The distribution of cinnarizine and its metabolites in the rat. Life Sci. 1968 Sep 1;7(17):989–994. [PubMed]
  • Barnes AJ, Locke P, Scudder PR, Dormandy TL, Dormandy JA, Slack J. Is hyperviscosity a treatable component of diabetic microcirculatory disease? Lancet. 1977 Oct 15;2(8042):789–791. [PubMed]
  • Dormandy JA, Hoare E, Colley J, Arrowsmith DE, Dormandy TL. Clinical, haemodynamic, rheological, and biochemical findings in 126 patients with intermittent claudication. Br Med J. 1973 Dec 8;4(5892):576–581. [PMC free article] [PubMed]
  • Dormandy JA, Hoare E, Khattab AH, Arrowsmith DE, Dormandy TL. Prognostic significance of rheological and biochemical findings in patients with intermittent claudication. Br Med J. 1973 Dec 8;4(5892):581–583. [PMC free article] [PubMed]
  • Elkeles A. Alpha-ray activity in the large human arteries. Nature. 1969 Feb 15;221(5181):662–664. [PubMed]
  • Godfraind T, Kaba A. Blockade or reversal of the contraction induced by calcium and adrenaline in depolarized arterial smooth muscle. Br J Pharmacol. 1969 Jul;36(3):549–560. [PMC free article] [PubMed]
  • Godfraind T, Kaba A, Rojas R. Proceedings: Inhibition by cinnarizine of calcium channels opening in depolarized smooth muscle. Br J Pharmacol. 1973 Sep;49(1):164P–165P. [PMC free article] [PubMed]
  • Godfraind T, Morel N. An upper limit to the number of calcium channels in smooth muscle as estimated with cinnarizine. Eur J Pharmacol. 1977 Jan 21;41(2):245–246. [PubMed]
  • Goyle KB, Dormandy JA. Abnormal blood viscosity in Raynaud's phenomenon. Lancet. 1976 Jun 19;1(7973):1317–1318. [PubMed]
  • Errill EW. Rheology of blood. Physiol Rev. 1969 Oct;49(4):863–888. [PubMed]
  • PHILIPSZOON AJ. Influence of cinnarizine on the labyrinth and on vertigo. Clin Pharmacol Ther. 1962 Mar-Apr;3:184–190. [PubMed]
  • Put T. The therapeutic value of cinnarizine in cervico-brachial and ischial syndromes. Arzneimittelforschung. 1969 Nov;19(11):1868–1869. [PubMed]
  • Rosenblum WI. "Viscosity-plus" effect in whole blood at high shear rates. Nature. 1969 Jan 25;221(5178):365–366. [PubMed]
  • Ross R, Glomset JA. The pathogenesis of atherosclerosis (first of two parts). N Engl J Med. 1976 Aug 12;295(7):369–377. [PubMed]
  • Schmitt G, Skrobek R, Hauss WH. Uber die Wirkung von Cinnarizin (Stutgeron) auf die hochdruckbedingte Zellproliferation in Herz und Aorta im Tierexperiment. Med Welt. 1974 Jun 14;25(24):1096–1099. [PubMed]
  • Schuermans V, Boermans A, Geivers H, Jageneau A, Brugmans J. Cinnarizine in peripheral vascular insufficiency. Studies on blood flow, muscle capacity, and vascular tone. Arzneimittelforschung. 1971 Oct;21(10):1541–1543. [PubMed]
  • Soudijn W, Van Wijngaarden I. The metabolism and excretion of cinnarizine by rats. Life Sci. 1968 Mar 1;7(5):231–238. [PubMed]
  • TRUMBULL R, CHINN HI, MAAG CH, MILCH LJ, HANDFORD SW, SEIBERT R, SPERLING P, SMITH PK. Effect of certain drugs on the incidence of seasickness. Clin Pharmacol Ther. 1960 May-Jun;1:280–283. [PubMed]
  • Van Nueten JM, Janssen PA. Effect of cinnarizine on peripheral circulation in dogs. Eur J Pharmacol. 1972 Jan;17(1):103–106. [PubMed]
  • Verhaegen H, Roels V, Adriaensen H, Brugmans J, De Cock W, Dony J, Jageneau A, Schuermans V. The arteriolar effects of cinnarizine and flunarizine. Multitechnical investigations in normal volunteers and in patients with occlusive disease of the extremities secondary to arteriosclerosis. Angiology. 1974 Apr;25(4):261–278. [PubMed]
  • Weed RI, Bowdler AJ. Metabolic dependence of the critical hemolytic volume of human erythrocytes: relationship to osmotic fragility and autohemolysis in hereditary spherocytosis and normal red cells. J Clin Invest. 1966 Jul;45(7):1137–1149. [PMC free article] [PubMed]
  • Weed RI, LaCelle PL, Merrill EW. Metabolic dependence of red cell deformability. J Clin Invest. 1969 May;48(5):795–809. [PMC free article] [PubMed]

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