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Arthritis Res. 2002; 4(6): 346–352.
Published online Sep 18, 2002.
PMCID: PMC153843

Interferon-β for treatment of rheumatoid arthritis?

Abstract

IFN-β treatment is emerging as a potentially effective form of therapy in various immune-mediated conditions. The present review addresses the possible role of IFN-β in immune-mediated diseases such as multiple sclerosis and rheumatoid arthritis. Several placebo-controlled trials are discussed, as are the available immunological data that are relevant to this field. Review of these data provides evidence that IFN-β has some beneficial therapeutic effect in patients with relapsing-remitting multiple sclerosis and might also have antirheumatic potential. This notion is supported by recent studies showing a critical role for IFN-β in bone homeostasis.

Keywords: IFN-β, multiple sclerosis, rheumatoid arthritis

Articles from Arthritis Research are provided here courtesy of BioMed Central