The rapidly expanding biological datasets of physical, genetic and functional interactions present a daunting task for data visualization and evaluation [1
]. Existing applications such as Pajek allow the user to visualize networks in a simple graphical format [2
], but lack the necessary features needed for functional assessment and comparative analysis between datasets. Typically, interaction networks are viewed within a graphing application, but data is manipulated in other contexts, often manually.
To address these shortfalls, we developed a network visualization system called Osprey that not only represents interactions in a flexible and rapidly expandable graphical format, but also provides options for functional comparisons between datasets. Osprey was developed with the Sun Microsystems Java Standard Development Kit version 1.4.0_02 [3
], which allows it to be used both in stand-alone form and as an add-on viewer for online interaction databases.