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J R Soc Med. 1982; 75(Suppl 1): 36–39.
PMCID: PMC1440496

Enflurane analgesia

Abstract

An air–enflurane mixture was used for inhalation analgesia in conscious patients undergoing painful procedures such as burns dressings. A preliminary study indicated that enflurane possessed definite analgesic properties, but that the concentration of the air–enflurane mixture was critical if restlessness was to be avoided and cooperation retained. Further studies established that 1% enflurane in air provided good analgesia in the absence of anaesthesia. The analgesic effects were similar to those produced by 0.35% methoxyflurane in air, but were produced in a much shorter time (about 3 minutes compared with 9 to 10 minutes). Preoperative starvation was unnecessary and nausea and vomiting were absent. Details are given of the use of enflurane analgesia in 32 conscious burned patients who underwent 101 burns dressing procedures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • ARTUSIO JF., Jr Di-ethyl ether analgesia: a detailed description of the first stage of ether anesthesia in man. J Pharmacol Exp Ther. 1954 Jul;111(3):343–348. [PubMed]
  • Firn S. Methoxyflurane analgesia for burns dressings and other painful ward procedures in children. Br J Anaesth. 1972 May;44(5):517–522. [PubMed]
  • Laird SM, Gray BM. Intermittent inhalation of methoxyflurane and trichloroethylene as analgesics in burns dressings procedures. Br J Anaesth. 1971 Feb;43(2):149–159. [PubMed]
  • Marshall MA, Ozorio HP. Analgesia for burns dressing using methoxyflurane. Br J Anaesth. 1972 Jan;44(1):80–82. [PubMed]
  • Packer KJ, Titel JH. Methoxyflurane analgesia for burns dressings: experience with the analgizer. Br J Anaesth. 1969 Dec;41(12):1080–1085. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press