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J R Soc Med. 1984 December; 77(12): 1002–1005.
PMCID: PMC1440165

Predictors of outcome at two years in patients with rheumatoid arthritis.


The prognostic value of clinical and laboratory measures in 72 patients with rheumatoid arthritis (RA), seen initially within 18 months of disease onset, in predicting function outcome after a further two years was assessed. Limitation of wrist extension was associated with a slow disease onset, a high articular index and a high latex titre. A reduction in global functional capacity, as measured by the Stanford Health Assessment Questionnaire, was associated with a high initial articular index and a high latex titre. Neither outcome was associated with the initial level of acute phase reactants nor with patient or physician's initial assessment of disease activity. It is concluded, first, that factors predicting early disability outcome in RA are not identical to those associated with continuing disease activity; and secondly, that patients' and physicians' judgment of disease activity at diagnosis do not carry any prognostic value for functional outcome two years later.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Fleming A, Crown JM, Corbett M. Prognostic value of early features in rheumatoid disease. Br Med J. 1976 May 22;1(6020):1243–1245. [PMC free article] [PubMed]
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  • ROPES MW, BENNETT GA, COBB S, JACOX R, JESSAR RA. 1958 Revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis. 1958 Dec;9(4):175–176. [PubMed]

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