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J R Soc Med. 1984 February; 77(2): 111–113.
PMCID: PMC1439692

Cryosurgery for the urethral syndrome.


A technique is described for treating the urethral syndrome in ambulant women by cryosurgery under local anaesthesia using a specially devised guard or applicator. This follows a trial study (Parkes & Boreham 1980) in which a modified guard was used. Experience with over 350 cases and detailed follow up of 111 of them has confirmed improvement in 95% (93 of 111). No patient was made worse, only 10 required second treatments and the majority, when asked, said they thought the treatment was of value and that they would be prepared to have the same treatment again if necessary. This is a simple, safe and harmless technique for the treatment of the female urethral syndrome. It can be carried out under local anaesthesia as an outpatient or under general anaesthesia following cystoscopy. It causes few complications and relieves the symptoms in the majority of such patients.

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Selected References

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  • Farrar DJ, Green NA, Ashken MH. An evaluation of Otis urethrotomy in female patients with recurrent urinary tract infections. Br J Urol. 1973 Dec;45(6):610–615. [PubMed]
  • Hendry WF, Stanton SL, Williams DI. Recurrent urinary infections in girls: effects of urethral dilatation. Br J Urol. 1973 Feb;45(1):72–83. [PubMed]
  • Kapland GW, Sammons TA, King LR. A blind comparison of dilatation, urethrotomy and medication alone in the treatment of urinary tract infection in girls. J Urol. 1973 May;109(5):917–919. [PubMed]
  • Parkes AC, Boreham P. Cryosurgery for the urethral syndrome: preliminary communication. J R Soc Med. 1980 Jun;73(6):428–430. [PMC free article] [PubMed]
  • Rees DL, Whitfield HN, Islam AK, Doyle PT, Mayo ME, Wickham JE. Urodynamic findings in adult females with frequency and dysuria. Br J Urol. 1975;47(7):853–860. [PubMed]
  • Richardson FH, Stonington OG. Urethrolysis and external urethroplasty in the female. Surg Clin North Am. 1969 Dec;49(6):1201–1208. [PubMed]
  • Splatt AJ, Weedon D. The urethral syndrome: experience with the Richardson urethroplasty. Br J Urol. 1977 Apr;49(2):173–176. [PubMed]

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