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J R Soc Med. 1983 September; 76(9): 740–742.
PMCID: PMC1439410

Extraurinary manifestations of chronic pyonephrosis.


Twenty-five patients who underwent nephrectomy for chronic pyonephrosis were studied retrospectively. Such patients may present with a wide range of symptoms. Marked haematological and biochemical abnormalities are found, the most striking being a gross elevation of plasma viscosity (or ESR) and a raised alkaline phosphatase. The resulting picture often suggests extrarenal disease, and diagnostic confusion occurred in a number of patients.

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Selected References

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  • Gingell JC, Roylance J, Davies ER, Penry JB. Xanthogranulomatous pyelonephritis. Br J Radiol. 1973 Feb;46(542):99–109. [PubMed]
  • Kirk D. Silent pyonephrosis as a cause of chronic ill-health. Lancet. 1982 Mar 27;1(8274):705–707. [PubMed]
  • Neale G, Caughey DE, Mollin DL, Booth CC. Effects of intrahepatic and extrahepatic infection on liver function. Br Med J. 1966 Feb 12;1(5484):382–387. [PMC free article] [PubMed]
  • Vermillion SE, Morlock CG, Bartholomew LG, Kelalis PP. Nephrogenic hepatic dysfunction: secondary to tumefactive xanthogranulomatous pyelonephritis. Ann Surg. 1970 Jan;171(1):130–136. [PubMed]

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