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J R Soc Med. 1981 November; 74(11): 804–809.
PMCID: PMC1439365

Cryoanalgesia for intractable perineal pain.


Cryoanalgesia, the local application of extreme cold to nerves to produce analgesia, has been used to treat patients with intractable perineal pain. The cryoprobe was inserted percutaneously through the sacral hiatus into the sacral canal to produce anaesthesia of the lower sacral nerve roots. Forty patients received a total of 70 treatments: 31 patients (78%) were helped by the procedure and the median duration of improvement was 30 days. The treatment was more successful in relieving symptoms in patients suffering from pelvic cancer and coccydynia. The best results were obtained in those patients who received numerous freeze applications or prolonged freezing.

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Selected References

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  • Barnard JD, Lloyd JW, Glynn CJ. Cryosurgery in the management of intractable facial pain. Br J Oral Surg. 1978 Nov;16(2):135–142. [PubMed]
  • Beazley RM, Bagley DH, Ketcham AS. The effect of cryosurgery on peripheral nerves. J Surg Res. 1974 Mar;16(3):231–234. [PubMed]
  • Evans PJ, Lloyd JW, Green CJ. Cryoanalgesia technique. Lancet. 1980 May 31;1(8179):1188–1189. [PubMed]
  • Smith JJ, Fraser J. An estimation of tissue damage and thermal history in the cryolesion. Cryobiology. 1974 Apr;11(2):139–147. [PubMed]
  • SUNDERLAND S. A classification of peripheral nerve injuries producing loss of function. Brain. 1951 Dec;74(4):491–516. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press