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J R Soc Med. 1981 July; 74(7): 492–498.
PMCID: PMC1439031

Oral complaints related to climacteric symptoms in oöphorectomized women.


Numerous oral complaints have been attributed to the female climacteric including altered taste, a burning sensation and xerostomia. However, the data relating these symptoms to the climacteric require elucidation as there have been no adequately controlled studies. In the present investigation, a group of 145 oöphorectomized women were followed for one year. Approximately half were treated with oestrogen replacement and the remainder with a placebo. The results indicate that the hormone had no direct effect upon the oral symptoms but that there was a general increase in somatic complaints which appeared to be related to the degree of neurosis experienced. This is turn can be attributed to vasomotor changes which are under the control of oestrogen.

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Selected References

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  • Basker RM, Sturdee DW, Davenport JC. Patients with burning mouths. A clinical investigation of causative factors, including the climacteric and diabetes. Br Dent J. 1978 Jul 4;145(1):9–16. [PubMed]
  • BLATT MHG, WIESBADER H, KUPPERMAN HS. Vitamin E and climacteric syndrome; failure of effective control as measured by menopausal index. AMA Arch Intern Med. 1953 Jun;91(6):792–799. [PubMed]
  • Greene JG. A factor analytic study of climacteric symptoms. J Psychosom Res. 1976;20(5):425–430. [PubMed]
  • IUSEM R. A cytology study of the cornification of the oral mucosa in women. A preliminary report. Oral Surg Oral Med Oral Pathol. 1950 Dec;3(12):1516–1520. [PubMed]
  • Kellner R, Sheffield BF. A self-rating scale of distress. Psychol Med. 1973 Feb;3(1):88–100. [PubMed]
  • Klinger G, Klinger G. Untersuchungen über den Einfluss oraler Kontrazeptiva auf die Mund- und Vaginalschleimhaut. Dtsch Stomatol. 1970 Sep;20(9):664–669. [PubMed]
  • Lindsay R, Hart DM, Aitken JM, MacDonald EB, Anderson JB, Clarke AC. Long-term prevention of postmenopausal osteoporosis by oestrogen. Evidence for an increased bone mass after delayed onset of oestrogen treatment. Lancet. 1976 May 15;1(7968):1038–1041. [PubMed]
  • Louridis O, Demetriou N, Mavrikaki M. Observations clinique sur l'étiopathogénie et la thérapeutique des glosodynies. Rev Stomatol Chir Maxillofac. 1971 Mar;72(2):296–297. [PubMed]
  • Main DM, Ritchie GM. Cyclic changes in oral smears from young menstruating women. Br J Dermatol. 1967 Jan;79(1):20–30. [PubMed]
  • MASSLER M. Oral manifestations during the female climacteric (the postmenopausal syndrome). Oral Surg Oral Med Oral Pathol. 1951 Oct;4(10):1234–1243. [PubMed]
  • Pisanty S, Rafaely B, Polishuk W. The effect of steroid hormones on buccal mucosa of menopausal women. Oral Surg Oral Med Oral Pathol. 1975 Sep;40(3):346–353. [PubMed]
  • Schoenberg B, Carr AC, Kutscher AH, Zegarelli EV. Chronic idiopathic orolingual pain. Psychogenesis of burning mouth. N Y State J Med. 1971 Aug 1;71(15):1832–1837. [PubMed]
  • Storer R. The effect of the climacteric and of ageing on prosthetic diagnosis and treatment planning. Br Dent J. 1965 Oct 19;119(8):349–354. [PubMed]
  • TROTT JR. A desquamative cytological study of healthy oral mucosa. Acta Anat (Basel) 1962;49:289–296. [PubMed]

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