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J R Soc Med. 1981 August; 74(8): 574–579.
PMCID: PMC1438896

Selection of patients with chronic drug-resistant epilepsy for resective surgery: 5 years' experience1


Selection criteria are the key to success in resective surgery for intractable epilepsy. Using such criteria about 50% of patients admitted for assessment are considered unsuitable, half of these for neurophysiological reasons or because there is evidence of more than one area of structural abnormality. Selection for a good result from temporal lobectomy can be judged, both on the proportion of positive pathological lesions in the resected temporal lobes and on a high degree of seizure relief together with a low incidence of side effects. The same holds for other resections. The relationship between these factors is reviewed.

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Selected References

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  • Falconer MA. Genetic and related aetiological factors in temporal lobe epilepsy. A review. Epilepsia. 1971 Mar;12(1):13–31. [PubMed]
  • Falconer MA. Reversibility by temporal-lobe resection of the behavioral abnormalities of temporal-lobe epilepsy. N Engl J Med. 1973 Aug 30;289(9):451–455. [PubMed]
  • KRYNAUW RA. Infantile hemiplegia treated by removing one cerebral hemisphere. J Neurol Neurosurg Psychiatry. 1950 Nov;13(4):243–267. [PMC free article] [PubMed]
  • Polkey CE. Selection of patients with intractable epilepsy for resective surgery. Arch Dis Child. 1980 Nov;55(11):841–844. [PMC free article] [PubMed]
  • Polkey CE. Surgery for epilepsy. Br J Hosp Med. 1981 Jan;25(1):48–57. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press