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J R Soc Med. 1981 May; 74(5): 357–362.
PMCID: PMC1438816

Captopril for refractory hypertension in patients with chronic renal failure and renal transplantation.


The converting-enzyme inhibitor, captopril, was given to ten patients with refractory severe hypertension of renal origin: 6 patients had chronic renal failure, 3 patients had hypertension following renal transplantation, and one patient had hypertension and congestive cardiac failure. Control of blood pressure was achieved with doses from 78 to 400 mg/day. Severe hyperkalaemia occurred in one patients, ageusia (dose dependent) in another, and one patients withdrew from treatment because of nausea.

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Selected References

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