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J R Soc Med. 1982 November; 75(11): 875–878.
PMCID: PMC1438451

Systemic candidiasis: diagnosis from cutaneous manifestations.


Three patients are described who developed systemic candidiasis. Each had either leukaemia or lymphoma, and developed a similar erythematous maculopapular rash which, in places, was purpuric. In the first patient the nature of the rash was not appreciated during life, but postmortem histology revealed candida within the lesions. In the other two patients, a diagnosis of systemic candidiasis was successfully established by skin biopsy. This paper emphasizes that a maculopapular rash can be relatively characteristic clinical manifestation of systemic candidiasis and that skin biopsy can be diagnostic.

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Selected References

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  • Balandran L, Rothschild H, Pugh N, Seabury J. A cutaneous manifestation of systemic candidiasis. Ann Intern Med. 1973 Mar;78(3):400–403. [PubMed]
  • Bodey GP. Fungal infections complicating acute leukemia. J Chronic Dis. 1966 Jun;19(6):667–687. [PubMed]
  • Bodey GP, Luna M. Skin lesions associated with disseminated candidiasis. JAMA. 1974 Sep 9;229(11):1466–1468. [PubMed]
  • Preisler HD, Hasenclever HF, Levitan AA, Henderson ES. Serologic diagnosis of disseminated candidiasis in patients with acute leukemia. Ann Intern Med. 1969 Jan;70(1):19–30. [PubMed]

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