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J R Soc Med. 1981 January; 74(1): 53–55.
PMCID: PMC1438326

Coagulation abnormalities in fatal cerebral lupus erythematosus.

Abstract

Two cases of fatal systemic lupus erythematosus (SLE) with cerebral involvement are described. Both showed widespread microinfarction of the brain secondary to platelet and fibrin thrombi. There was no evidence of vasculitis. Anticoagulants and antiplatelet drugs may have an important role in the management of cerebral SLE.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Bluestein HG, Zvaifler NJ. Brain-reactive lymphocytotoxic antibodies in the serum of patients with systemic lupus erythematosus. J Clin Invest. 1976 Feb;57(2):509–516. [PMC free article] [PubMed]
  • Johnson RT, Richardson EP. The neurological manifestations of systemic lupus erythematosus. Medicine (Baltimore) 1968 Jul;47(4):337–369. [PubMed]
  • LEVINE S, SHEARN MA. THROMBOTIC THROMBOCYTOPENIC PURPURA AND SYSTEMIC LUPUS ERYTHEMATOSUS. Arch Intern Med. 1964 Jun;113:826–836. [PubMed]
  • Pinching AJ, Travers RL, Hughes GR, Jones T, Moss S. Oxygen-15 brain scanning for detection of cerebral involvement in systemic lupus erythematosus. Lancet. 1978 Apr 29;1(8070):898–900. [PubMed]
  • Timperley WR, Preston FE, Ward JD. Cerebral intravascular coagulation in diabetic ketoacidosis. Lancet. 1974 May 18;1(7864):952–956. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press