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J R Soc Med. 1982 July; 75(7): 530–532.
PMCID: PMC1437893

Diabetes mellitus with ketoacidosis presenting as Fournier's gangrene.


Two patients with Fournier's gangrene are described. In each case this was the presenting clinical feature of diabetes mellitus with ketoacidosis. Histological examination demonstrated that the probable cause was intravascular fibrin deposition. The association between diabetes mellitus and Fournier's gangrene is discussed.

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Selected References

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  • Gerber MP, Peterson NE. Scrotal gangrene. Urology. 1973 May;1(5):466–469. [PubMed]
  • Jones RB, Hirschmann JV, Brown GS, Tremann JA. Fournier's syndrome: necrotizing subcutaneous infection of the male genitalia. J Urol. 1979 Sep;122(3):279–282. [PubMed]
  • Rudolph R, Soloway M, DePalma RG, Persky L. Fournier's syndrome: synergistic gangrene of the scrotum. Am J Surg. 1975 May;129(5):591–596. [PubMed]
  • Timperley WR, Preston FE, Ward JD. Cerebral intravascular coagulation in diabetic ketoacidosis. Lancet. 1974 May 18;1(7864):952–956. [PubMed]

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