Search tips
Search criteria 


Logo of jrsocmedLink to Publisher's site
J R Soc Med. 1980 July; 73(7): 501–504.
PMCID: PMC1437717

Antibodies against defined nerve cell components: gangliosides1


Antisera have been raised in rabbits against the purified brain gangliosides GM1, GD1a and GT1b. The reactivity of these sera with a range of purified gangliosides has been examined by complement fixation and their specificities partially defined by absorptions with purified gangliosides.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (507K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Coulon-Morelec MJ, Faure M, Maréchal J. Haptènes lipidiques. Etude du pouvoir immunisant du mono- et du di-palmityl-glycéryl-glucuronoside additionnés de cholestérol et d'albumine. Ann Inst Pasteur (Paris) 1970 Jul;119(1):17–26. [PubMed]
  • FOLCH J, LEES M, SLOANE STANLEY GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957 May;226(1):497–509. [PubMed]
  • Gregson NA, Kennedy MC, Leibowitz S. Immunological reactions with lysolecithin-solubilized myelin. Immunology. 1971 Apr;20(4):501–512. [PubMed]
  • Iwamori M, Nagai Y. A new chromatographic approach to the resolution of individual gangliosides. Ganglioside mapping. Biochim Biophys Acta. 1978 Feb 27;528(2):257–267. [PubMed]
  • Karpiak SE, Graf L, Rapport MM. Antibodies to GM1 ganglioside inhibit a learned avoidance response. Brain Res. 1978 Aug 11;151(3):637–640. [PubMed]
  • Kundu SK, Marcus DM, Veh RW. Preparation and properties of antibodies to GD3 and GM1 gangliosides. J Neurochem. 1980 Jan;34(1):184–188. [PubMed]
  • Naiki M, Marcus DM, Ledeen R. Properties of antisera to ganglioside GM1 and asialo GM1. J Immunol. 1974 Jul;113(1):84–93. [PubMed]
  • Pascal TA, Saifer A. Immunochemical studies of isolated human brain ganglioside components. J Neurochem. 1969 Mar;16(3):301–307. [PubMed]
  • RAPPORT MM, GRAF L, YARIV J. Immunochemical studies of organ and tumor lipids. IX. Configuration of the carbohydrate residues in cytolipin H. Arch Biochem Biophys. 1961 Mar;92:438–440. [PubMed]
  • Veh R, Corfield AP, Sander M, Schauer R. Neuraminic acid-specific modification and tritium labelling of gangliosides. Biochim Biophys Acta. 1976 Jan 18;486(1):145–160. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press