Search tips
Search criteria 


Logo of jrsocmedLink to Publisher's site
J R Soc Med. 1982 January; 75(1): 27–30.
PMCID: PMC1437381

Medicament contact dermatitis in patients with chronic inflammatory ear disease.


Patch testing of 40 patients with chronic inflammatory ear disease demonstrated medicament allergic contact dermatitis in 35%. The most frequent sensitizers were neomycin, framycetin, clioquinol and gentamicin. Although allergic contact dermatitis to dewaxing ear drops was unusual, irritant reactions were common.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (449K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Boxley JD, Dawber RP. Contact dermatitis to one ingredient of Xerumenex ear drops. Contact Dermatitis. 1976 Aug;2(4):233–234. [PubMed]
  • Bandmann HJ, Calnan CD, Cronin E, Fregert S, Hjorth N, Magnusson B, Maibach H, Malten KE, Meneghini CL, Pirilä V, et al. Dermatitis from applied medicaments. Arch Dermatol. 1972 Sep;106(3):335–337. [PubMed]
  • Carruthers JA, Cronin E. Incidence of neomycin and framycetin sensitivity. Contact Dermatitis. 1976 Oct;2(5):269–270. [PubMed]
  • FREGERT S. Otitis externa due to chromate of matches. Acta Derm Venereol. 1962;42:473–475. [PubMed]
  • Grice K, Johnstone CI. Contact dermatitis from Xerumenex. Br Med J. 1972 Feb 19;1(5798):508–508. [PMC free article] [PubMed]
  • Hjorth N, Thomsen K. Patch tests with neomycin. Time of reaction. Patch test sensitizations. Acta Allergol. 1966;21(6):487–496. [PubMed]
  • Jensen OC, Allen HJ, Mordecai LR. Neomycin contact dermatitis superimposed on otitis externa. JAMA. 1966 Jan 10;195(2):131–133. [PubMed]
  • Kligman AM. The identification of contact allergens by human assay. 3. The maximization test: a procedure for screening and rating contact sensitizers. J Invest Dermatol. 1966 Nov;47(5):393–409. [PubMed]
  • McKelvie M, McKelvie P. Some aetiological factors in otitis externa. Br J Dermatol. 1966 Apr;78(4):227–231. [PubMed]
  • Pirilä V, Hirvonen ML, Rouhunkoski S. The pattern of cross-sensitivity to neomycin. Secondary sensitization to gentamicin. Dermatologica. 1968;136(5):321–324. [PubMed]
  • Wilkinson JD, Hambly EM, Wilkinson DS. Comparison of patch test results in two adjacent areas of England. II. Medicaments. Acta Derm Venereol. 1980;60(3):245–249. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press