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J R Soc Med. 1982 January; 75(1): 21–22.
PMCID: PMC1437371

Buscopan or glucagon for endoscopic cannulation of ampulla of vater?


The number of intravenous injections of hyoscine-N-butylbromide (Buscopan) or glucagon required to maintain relaxation of the duodenum during endoscopic retrograde cholangiopancreatography (ERCP) were compared in a double blind trial of 55 patients. There was no significant difference in the number of injections. Serum amylase levels after the use of both relaxants were compared in 50 patients undergoing ERCP. No significant difference in the levels of hyperamylasaemia were found.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Bilbao MK, Dotter CT, Lee TG, Katon RM. Complications of endoscopic retrograde cholangiopancreatography (ERCP). A study of 10,000 cases. Gastroenterology. 1976 Mar;70(3):314–320. [PubMed]
  • Condon JR, Knight M, Day JL. Glucagon therapy in acute pancreatitis. Br J Surg. 1973 Jul;60(7):509–511. [PubMed]
  • Cotton PB. ERCP. Gut. 1977 Apr;18(4):316–341. [PMC free article] [PubMed]
  • Dürr HK, Maroske D, Zelder O, Bode JC. Glucagon therapy in acute pancreatitis. Report of a double-blind trial. Gut. 1978 Mar;19(3):175–179. [PMC free article] [PubMed]
  • Skude G, Wehlin L, Maruyama T, Ariyama J. Hyperamylasaemia after duodenoscopy and retrograde cholangiopancreatography. Gut. 1976 Feb;17(2):127–132. [PMC free article] [PubMed]

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