Search tips
Search criteria 


Logo of jrsocmedLink to Publisher's site
J R Soc Med. 1978 August; 71(8): 591–595.
PMCID: PMC1436566

Trichlorethylene – relationship of metabolite levels to atmospheric concentrations: preliminary communication1


The search for a practical index of trichlorethylene exposure must take into account its degree of narcotic activity in turn related to air concentration. Trichloracetic acid level in urine provides a useful means of assessing exposure and it can be related to trichlorethylene in air. A small investigation of this relationship has been carried out on two continuously exposed subjects.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (557K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • ANDERSSON A. Gesundheitliche Gefahren in der Industrie bei Exposition für Trichloräthylen; eine klinische, experimentelle und gewerbehygienische Untersuchung. Acta Med Scand Suppl. 1957;323:1–220. [PubMed]
  • BARTONICEK V. Metabolism and excretion of trichloroethylene after inhalation by human subjects. Br J Ind Med. 1962 Apr;19:134–141. [PMC free article] [PubMed]
  • BELL A. Death from trichlorethylene in a dry-cleaning establishment. N Z Med J. 1951 Apr;50(276):119–126. [PubMed]
  • CHALUPA B, SYNKOVA J, SEVCIK M. The assessment of electroencephalographic changes and memory disturbances in acute intoxications with industrial poisons. Br J Ind Med. 1960 Jul;17:238–241. [PMC free article] [PubMed]
  • FRANT R, WESTENDORP J. Medical control on exposure of industrial workers to trichloroethylene. Arch Ind Hyg Occup Med. 1950 Mar;1(3):308–318. [PubMed]
  • FRIBERG L, KYLIN B, NYSTROM A. Toxicities of trichlorethylene and tetrachloroethylene and Fujiwara's pyridine-alkali reaction. Acta Pharmacol Toxicol (Copenh) 1953;9(4):303–312. [PubMed]
  • GRANDJEAN E, MUNCHINGER R, TURRIAN V, HASS PA, KNOEPFEL HK, ROSENMUND H. Investigations into the effects of exposure to trichlorethylene in mechanical engineering. Br J Ind Med. 1955 Apr;12(2):131–142. [PMC free article] [PubMed]
  • HOSCHEK R. [Sudden late death after slight trichloroethyle effect]. Int Arch Gewerbepathol Gewerbehyg. 1962 Jun 12;19:319–328. [PubMed]
  • Milby TH. Chronic trichloroethylene intoxication. J Occup Med. 1968 May;10(5):252–254. [PubMed]
  • Ogata M, Takatsuka Y, Tomokuni K. A simple method for the quantitative analysis of urinary trichloroethanol and trichloroacetic acid as an index of trichloroethylene exposure. Br J Ind Med. 1970 Oct;27(4):378–381. [PMC free article] [PubMed]
  • RIVOIRE J, GENEVOIS M, TOLOT F. [Elimination of trichloroacetic acid in subjects exposed to trichloroethylene. Results of the routine use of this method in an industrial plant]. Arch Mal Prof. 1962 Jun;23:395–399. [PubMed]
  • SOUCEK B, VLACHOVA D. Excretion of trichloroethylene metabolites in human urine. Br J Ind Med. 1960 Jan;17:60–64. [PMC free article] [PubMed]
  • Stewart RD, Hake CL, Peterson JE. Use of breath analysis to monitor trichloroethylene exposures. Arch Environ Health. 1974 Jul;29(1):6–13. [PubMed]
  • Tanaka S, Ikeda M. A method for determination of trichloroethanol and trichloroacetic acid in urine. Br J Ind Med. 1968 Jul;25(3):214–219. [PMC free article] [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press