PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jrsocmedLink to Publisher's site
 
J R Soc Med. 1978 November; 71(11): 809–818.
PMCID: PMC1436187

Hypothesis into theory--the development of aetiological concepts of ischaemic heart disease: a review.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.4M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Armstrong ML. Evidence of regression of atherosclerosis in primates and man. Postgrad Med J. 1976 Jul;52(609):456–461. [PMC free article] [PubMed]
  • Armstrong ML, Megan MB. Lipid depletion in atheromatous coronary arteries in rhesus monkeys after regression diets. Circ Res. 1972 Jun;30(6):675–680. [PubMed]
  • Avogaro P, Cazzolato G. Familial hyper-HDL-(a)-cholesterolemia. Atherosclerosis. 1975 Jul-Aug;22(1):63–77. [PubMed]
  • Balogh M, Kahn HA, Medalie JH. Random repeat 24-hour dietary recalls. Am J Clin Nutr. 1971 Mar;24(3):304–310. [PubMed]
  • BARCLAY M, BARCLAY RK, SKIPSKI VP. HIGH-DENSITY LIPOPROTEIN CONCENTRATIONS IN MEN AND WOMEN. Nature. 1963 Oct 26;200:362–363. [PubMed]
  • Barndt R, Jr, Blankenhorn DH, Crawford DW, Brooks SH. Regression and progression of early femoral atherosclerosis in treated hyperlipoproteinemic patients. Ann Intern Med. 1977 Feb;86(2):139–146. [PubMed]
  • BARR DP, RUSS EM, EDER HA. Protein-lipid relationships in human plasma. II. In atherosclerosis and related conditions. Am J Med. 1951 Oct;11(4):480–493. [PubMed]
  • Belfrage P, Berg B, Hägerstrand I, Nilsson-Ehle P, Tornqvist H, Wiebe T. Alterations of lipid metabolism in healthy volunteers during long-term ethanol intake. Eur J Clin Invest. 1977 Apr;7(2):127–131. [PubMed]
  • Benditt EP. Implications of the monoclonal character of human atherosclerotic plaques. Am J Pathol. 1977 Mar;86(3):693–702. [PubMed]
  • Benditt EP, Benditt JM. Evidence for a monoclonal origin of human atherosclerotic plaques. Proc Natl Acad Sci U S A. 1973 Jun;70(6):1753–1756. [PubMed]
  • Berg K, Borresen AL. Serum-high-density-lipoprotein and atherosclerotic heart-disease. Lancet. 1976 Mar 6;1(7958):499–501. [PubMed]
  • Berglund G, Sannerstedt R, Andersson O, Wedel H, Wilhelmsen L, Hansson L, Sivertsson R, Wikstrand J. Coronary heart-disease after treatment of hypertension. Lancet. 1978 Jan 7;1(8054):1–5. [PubMed]
  • Bierman EL, Albers JJ. Lipoprotein uptake by cultured human arterial smooth muscle cells. Biochim Biophys Acta. 1975 May 22;388(2):198–202. [PubMed]
  • Blackburn H. Concepts and controversies about the prevention of coronary heart disease. Postgrad Med J. 1976 Jul;52(609):417–423. [PMC free article] [PubMed]
  • Brown MS, Goldstein JL. Receptor-mediated control of cholesterol metabolism. Science. 1976 Jan 16;191(4223):150–154. [PubMed]
  • Brunzell JD, Schrott HG, Motulsky AG, Bierman EL. Myocardial infarction in the familial forms of hypertriglyceridemia. Metabolism. 1976 Mar;25(3):313–320. [PubMed]
  • Carew TE, Koschinsky T, Hayes SB, Steinberg D. A mechanism by which high-density lipoproteins may slow the atherogenic process. Lancet. 1976 Jun 19;1(7973):1315–1317. [PubMed]
  • Carlson LA, Böttiger LE. Ischaemic heart-disease in relation to fasting values of plasma triglycerides and cholesterol. Stockholm prospective study. Lancet. 1972 Apr 22;1(7756):865–868. [PubMed]
  • Carlson LA, Danielson M, Ekberg I, Klintemar B, Rosenhamer G. Reduction of myocardial reinfarction by the combined treatment with clofibrate and nicotinic acid. Atherosclerosis. 1977 Sep;28(1):81–86. [PubMed]
  • Carlson LA, Ekelund LG, Olsson AG. Frequency of ischaemic exercise E.C.G. Changes in symptom-free men with various forms of primary hyperlipaemia. Lancet. 1975 Jul 5;2(7923):1–3. [PubMed]
  • Carlson LA, Ericsson M. Quantitative and qualitative serum lipoprotein analysis. Part 2. Studies in male survivors of myocardial infarction. Atherosclerosis. 1975 May-Jun;21(3):435–450. [PubMed]
  • Carter CO, Slack J, Myant NB. Genetics of hyperlipoproteinaemias. Lancet. 1971 Feb 20;1(7695):400–401. [PubMed]
  • Castelli WP, Doyle JT, Gordon T, Hames CG, Hjortland MC, Hulley SB, Kagan A, Zukel WJ. Alcohol and blood lipids. The cooperative lipoprotein phenotyping study. Lancet. 1977 Jul 23;2(8030):153–155. [PubMed]
  • Chait A, Mancini M, February AW, Lewis B. Clinical and metabolic study of alcoholic hyperlipidaemia. Lancet. 1972 Jul 8;2(7767):62–64. [PubMed]
  • Chait A, Onitiri A, Nicoll A, Rabaya E, Davies J, Lewis B. Reduction of serum triglyceride levels by polyunsaturated fat. Studies on the mode of action and on very low density lipoprotein composition. Atherosclerosis. 1974 Sep-Oct;20(2):347–364. [PubMed]
  • Chen RM, Getz GS, Fischer-Dzoga K, Wissler RW. The role of hyperlipidemic serum on the proliferation and necrosis of aortic medial cells in vitro. Exp Mol Pathol. 1977 Jun;26(3):359–374. [PubMed]
  • Doll R, Peto R. Mortality in relation to smoking: 20 years' observations on male British doctors. Br Med J. 1976 Dec 25;2(6051):1525–1536. [PMC free article] [PubMed]
  • Dorr AE, Gundersen K, Schneider JC, Jr, Spencer TW, Martin WB. Colestipol hydrochloride in hypercholesterolemic patients--effect on serum cholesterol and mortality. J Chronic Dis. 1978 Jan;31(1):5–14. [PubMed]
  • Easty DL. The relationship of diet to serum cholesterol levels in young men in Antarctica. Br J Nutr. 1970 Mar;24(1):307–312. [PubMed]
  • Epstein FH. Risk factors in coronary heart disease--environmental and hereditary influences. Isr J Med Sci. 1967 Jul-Aug;3(4):594–607. [PubMed]
  • Epstein FH. Genetics of ischaemic heart disease. Postgrad Med J. 1976 Aug;52(610):477–480. [PMC free article] [PubMed]
  • Feinleib M. Discussion of: "Epidemiology of cardiovascular diseases: current perspectives". Am J Epidemiol. 1976 Oct;104(4):457–462. [PubMed]
  • Førde OH, Thelle DS, Miller NE, Mjøs OD. The Tromsø heart study. Distribution of serum cholesterol between high density and lower density lipoproteins in subjects of Norse, Finnish and Lappish ethnic origin. Acta Med Scand. 1978;203(1-2):21–26. [PubMed]
  • Fredrickson DS. It's time to be practical. Circulation. 1975 Feb;51(2):209–211. [PubMed]
  • Fredrickson DS. It's time to be practical. Circulation. 1975 Feb;51(2):209–211. [PubMed]
  • Fredrickson DS, Levy RI, Lees RS. Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med. 1967 Jan 26;276(4):215–contd. [PubMed]
  • Fredrickson DS, Levy RI, Lindgren FT. A comparison of heritable abnormal lipoprotein patterns as defined by two different techniques. J Clin Invest. 1969 Nov;47(11):2446–2457. [PMC free article] [PubMed]
  • Glomset JA. The plasma lecithins:cholesterol acyltransferase reaction. J Lipid Res. 1968 Mar;9(2):155–167. [PubMed]
  • Goldstein JL, Schrott HG, Hazzard WR, Bierman EL, Motulsky AG. Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia. J Clin Invest. 1973 Jul;52(7):1544–1568. [PMC free article] [PubMed]
  • Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med. 1977 May;62(5):707–714. [PubMed]
  • Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. Diabetes, blood lipids, and the role of obesity in coronary heart disease risk for women. The Framingham study. Ann Intern Med. 1977 Oct;87(4):393–397. [PubMed]
  • Gordon T, Thom T. The recent decrease in CHD mortality. Prev Med. 1975 Jun;4(2):115–125. [PubMed]
  • Goto Y, Sato SI, Masuda M. Causes of death in 3151 diabetic autopsy cases. Tohoku J Exp Med. 1974 Apr;112(4):339–353. [PubMed]
  • Grundy SM. Effects of polyunsaturated fats on lipid metabolism in patients with hypertriglyceridemia. J Clin Invest. 1975 Feb;55(2):269–282. [PMC free article] [PubMed]
  • Hammond EC, Garfinkel L. Coronary heart disease, stroke, and aortic aneurysm. Arch Environ Health. 1969 Aug;19(2):167–182. [PubMed]
  • Hazzard WR, Goldstein JL, Schrott MG, Motulsky AG, Bierman EL. Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction. J Clin Invest. 1973 Jul;52(7):1569–1577. [PMC free article] [PubMed]
  • Heady JA. Letter: Are PUFA harmful? Br Med J. 1974 Jan 19;1(5898):115–116. [PMC free article] [PubMed]
  • Hickey N, Mulcahy R, Bourke GJ, Graham I, Wilson-Davis K. Study of coronary risk factors related to physical activity in 15 171 men. Br Med J. 1975 Aug 30;3(5982):507–509. [PMC free article] [PubMed]
  • Jenkins DJ, Newton C, Leeds AR, Cummings JH. Effect of pectin, guar gum, and wheat fibre on serum-cholesterol. Lancet. 1975 May 17;1(7916):1116–1117. [PubMed]
  • Johnson B, Bye C, Labrooy J, Munro-Faure D, Slack J. Proceedings: The relation of antihypertensive treatment to plasma lipids and other vascular risk factors in hypertensives. Clin Sci Mol Med. 1974 Aug;47(2):9P–10P. [PubMed]
  • Keen H. Glucose intolerance, diabetes mellitus and atherosclerosis; prospects for prevention. Postgrad Med J. 1976 Jul;52(609):445–451. [PMC free article] [PubMed]
  • Kritchevsky D. Experimental atherosclerosis in primates and other species. Ann N Y Acad Sci. 1969 Jul 3;162(1):80–88. [PubMed]
  • Kushwaha RS, Hazzard WR, Wahl PW, Hoover JJ. Type III hyperlipoproteinemia: diagnosis in whole plasma by apolipoprotein-E immunoassay. Ann Intern Med. 1977 Nov;87(5):509–516. [PubMed]
  • Lewis B, Chait A, Oakley CM, Wootton ID, Krikler DM, Onitiri A, Sigurdsson G, February A. Serum lipoprotein abnormalities in patients with ischaemic heart disease: comparisons with a control population. Br Med J. 1974 Aug 24;3(5929):489–493. [PMC free article] [PubMed]
  • Lewis B, Chait A, Sigurdsson G. Serum lipoprotiens in four European communities: a quantitative comparison. Eur J Clin Invest. 1978 Jun;8(3):165–173. [PubMed]
  • Lewis B, Chait A, Wootton ID, Oakley CM, Krikler DM, Sigurdsson G, February A, Maurer B, Birkhead J. Frequency of risk factors for ischaemic heart-disease in a healthy British population. With particular reference to serum-lipoprotein levels. Lancet. 1974 Feb 2;1(7849):141–146. [PubMed]
  • Mann GV. Diet-Heart: end of an era. N Engl J Med. 1977 Sep 22;297(12):644–650. [PubMed]
  • McMichael J. Dietetic factors in coronary disease. Eur J Cardiol. 1977 Aug;5(6):447–452. [PubMed]
  • Miettinen TA, Lempinen M. Cholestyramine and ileal by-pass in the treatment of familial hypercholesterolaemia. Eur J Clin Invest. 1977 Dec;7(6):509–514. [PubMed]
  • Miettinen M, Turpeinen O, Karvonen MJ, Elosuo R, Paavilainen E. Effect of cholesterol-lowering diet on mortality from coronary heart-disease and other causes. A twelve-year clinical trial in men and women. Lancet. 1972 Oct 21;2(7782):835–838. [PubMed]
  • Miller KL. Post delivery care of the edentulous geriatric patient. Bull Phila Cty Dent Soc. 1975 Summer;40(8):16–19. [PubMed]
  • Miller NE, Thelle DS, Forde OH, Mjos OD. The Tromsø heart-study. High-density lipoprotein and coronary heart-disease: a prospective case-control study. Lancet. 1977 May 7;1(8019):965–968. [PubMed]
  • Miller NE, Nestel PJ, Clifton-Bligh P. Relationships between plasma lipoprotein cholesterol concentrations and the pool size and metabolism of cholesterol in man. Atherosclerosis. 1976 May-Jun;23(3):535–547. [PubMed]
  • Moutafis CD, Myant NB. The metabolism of cholesterol in two hypercholesterolaemic patients treated with cholestyramine. Clin Sci. 1969 Oct;37(2):443–454. [PubMed]
  • Nikkilä EA, Aro A. Family study of serum lipids and lipoproteins in coronary heart-disease. Lancet. 1973 May 5;1(7810):954–959. [PubMed]
  • Olefsky J, Reaven GM, Farquhar JW. Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects. J Clin Invest. 1974 Jan;53(1):64–76. [PMC free article] [PubMed]
  • Oliver MF, Nimmo IA, Cooke M, Carlson LA, Olsson AG. Ischaemic heart disease and associated risk factors in 40 year old men in Edinburgh and Stockholm. Eur J Clin Invest. 1975 Nov 21;5(6):507–514. [PubMed]
  • Onongbu IC, Lewis B. Lipoprotein fractionation by a precipitation method. A simple quantitative procedure. Clin Chim Acta. 1976 Sep 20;71(3):397–402. [PubMed]
  • Pelkonen R, Nikkilä EA, Koskinen S, Penttinen K, Sarna S. Association of serum lipids and obesity with cardiovascular mortality. Br Med J. 1977 Nov 5;2(6096):1185–1187. [PMC free article] [PubMed]
  • Pikkarainen J, Takkunen J, Kulonen E. Serum cholesterol in Finnish twins. Am J Hum Genet. 1966 Mar;18(2):115–126. [PubMed]
  • Rinzler SH. Primary prevention of coronary heart disease by diet. Bull N Y Acad Med. 1968 Aug;44(8):936–949. [PubMed]
  • Rissanen AM, Nikkilä EA. Coronary artery disease and its risk factors in families of young men with angina pectoris and in controls. Br Heart J. 1977 Aug;39(8):875–883. [PMC free article] [PubMed]
  • Roberts WC, Ferrans VJ, Levy RI, Fredrickson DS. Cardiovascular pathology in hyperlipoproteinemia. Anatomic observations in 42 necropsy patients with normal or abnormal serum lipoprotein patterns. Am J Cardiol. 1973 May;31(5):557–570. [PubMed]
  • Rose G. Detection of high coronary risk. Postgrad Med J. 1976 Jul;52(609):452–455. [PMC free article] [PubMed]
  • Ross R, Glomset J, Harker L. Response to injury and atherogenesis. Am J Pathol. 1977 Mar;86(3):675–684. [PubMed]
  • ROWSELL HC, DOWNIE HG, MUSTARD JF. The experimental production of atherosclerosis in swine following the feeding of butter and margarine. Can Med Assoc J. 1958 Oct 15;79(8):647–654. [PMC free article] [PubMed]
  • Rutherford RB, Ross R. Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate. J Cell Biol. 1976 Apr;69(1):196–203. [PMC free article] [PubMed]
  • Schrott HG, Goldstein JL, Hazzard WR, McGoodwin MM, Motulsky AG. Familial hypercholesterolemia in a large indred. Evidence for a monogenic mechanism. Ann Intern Med. 1972 May;76(5):711–720. [PubMed]
  • Shaper AG. Primary and secondary prevention trials in coronary heart disease. Postgrad Med J. 1976 Jul;52(609):464–469. [PMC free article] [PubMed]
  • Slack J. Risks of ischaemic heart-disease in familial hyperlipoproteinaemic states. Lancet. 1969 Dec 27;2(7635):1380–1382. [PubMed]
  • Sommariva D, Scotti L, Fasoli A. Low-fat diet versus low-carbohydrate diet in the treatment of type IV hyperlipoproteinaemia. Atherosclerosis. 1978 Jan;29(1):43–51. [PubMed]
  • Stone NJ, Levy RI, Fredrickson DS, Verter J. Coronary artery disease in 116 kindred with familial type II hyperlipoproteinemia. Circulation. 1974 Mar;49(3):476–488. [PubMed]
  • Sturdevant RA, Pearce ML, Dayton S. Increased prevalence of cholelithiasis in men ingesting a serum-cholesterol-lowering diet. N Engl J Med. 1973 Jan 4;288(1):24–27. [PubMed]
  • Truswell AS. Dietary fat and heart-disease. Lancet. 1977 Dec 3;2(8049):1173–1173. [PubMed]
  • Walker WJ. Changing United States life-style and declining vascular mortality: cause or coincidence? N Engl J Med. 1977 Jul 21;297(3):163–165. [PubMed]
  • Diet-heart era: premature obituary? N Engl J Med. 1978 Jan 12;298(2):106–110. [PubMed]
  • West RJ, Fosbrooke AS, Lloyd JK. Treatment of children with familial hypercholesterolaemia. Postgrad Med J. 1975;51(8):82–87. [PubMed]
  • Wilhelmsen L, Wedel H, Tibblin G. Multivariate analysis of risk factors for coronary heart disease. Circulation. 1973 Nov;48(5):950–958. [PubMed]
  • Wilson DE, Lees RS. Metabolic relationships among the plasma lipoproteins. Reciprocal changes in the concentrations of very low and low density lipoproteins in man. J Clin Invest. 1972 May;51(5):1051–1057. [PMC free article] [PubMed]
  • Wood PD, Haskell W, Klein H, Lewis S, Stern MP, Farquhar JW. The distribution of plasma lipoproteins in middle-aged male runners. Metabolism. 1976 Nov;25(11):1249–1257. [PubMed]
  • Zilversmit DB. A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins. Circ Res. 1973 Dec;33(6):633–638. [PubMed]

Articles from Journal of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press