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Gut. 1979 September; 20(9): 811–814.
PMCID: PMC1412643

Achalasia and diffuse oesophageal spasm in siblings.

Abstract

We report the occurrence of achalasia and diffuse oesophageal spasm in brother and sister. The familial occurrence of these unusual disorders is consistent with the possibility that they share a common aetiology and indicates the potential importance of genetic predisposition.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Binder HJ, Bloom DL, Stern H, Solitare GB, Thayer WR, Spiro HM. The effect of cervical vagectomy on esophageal function in the monkey. Surgery. 1968 Dec;64(6):1075–1083. [PubMed]
  • Kramer P, Fleshler B, McNally E, Harris LD. Oesophageal sensitivity to Mecholyl in symptomatic diffuse spasm. Gut. 1967 Apr;8(2):120–127. [PMC free article] [PubMed]
  • Kramer P, Harris LD, Donaldson RM., Jr Transition from symptomatic diffuse spasm to cardiospasm. Gut. 1967 Apr;8(2):115–119. [PMC free article] [PubMed]
  • KRAMER P, INGELFINGER FJ. Esophageal sensitivity to mecholyl in cardiospasm. Gastroenterology. 1951 Oct;19(2):242–253. [PubMed]
  • Mellow MH. Return of esophageal peristalsis in idiopathic achalasia. Gastroenterology. 1976 Jun;70(6):1148–1151. [PubMed]
  • Sanderson DR, Ellis FH, Jr, Schlegel JF, Olsen AM. Syndrome of vigorous achalasia: Clinical and physiologic observations. Dis Chest. 1967 Oct;52(4):508–517. [PubMed]

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