PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of gutGutView this articleSubmit a manuscriptReceive email alertsContact usBMJ
 
Gut. 1970 February; 11(2): 91–99.
PMCID: PMC1411356

Propulsion (mass movements) in the human colon and its relationship to meals and somatic activity

Abstract

Propulsive activity of the human colon was measured with radiopaque markers (shapes), radiotelemetering capsules, Perspex capsules containing 51Cr, or with free 51Cr sodium chromate.

Propulsive activity can be readily detected by these techniques, none of which requires the use of radiological contrast media. With capsules containing 51Cr or with free 51Cr repeated observations can be made in the same patient without recourse to radiography. The patient can remain normally active during the test with encapsulated 51Cr. Repeated observations may also be made with shapes, if films exposed at low mA are used.

It was found that colonic intraluminal pressure activity rises markedly during and after food, but that in the resting patient this increase is rarely associated with propulsive activity. In physically active patients propulsion of colonic contents was significantly increased after meals. When colonic propulsion takes place, it does so by a series of mass movements.

These results suggest that somatic activity is an important factor in the control of colonic transit in health or disease.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (2.8M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • CHAUDHARY NA, TRUELOVE SC. The irritable colon syndrome. A study of the clinical features, predisposing causes, and prognosis in 130 cases. Q J Med. 1962 Jul;31:307–322. [PubMed]
  • CONNELL AM, MCCALL J, MISIEWICZ JJ, ROWLANDS EN. OBSERVATIONS ON THE CLINICAL USE OF RADIO PILLS. Br Med J. 1963 Sep 28;2(5360):771–774. [PMC free article] [PubMed]
  • CONNELL AM, JONES FA, ROWLANDS EN. MOTILITY OF THE PELVIC COLON. IV. ABDOMINAL PAIN ASSOCIATED WITH COLONIC HYPERMOTILITY AFTER MEALS. Gut. 1965 Apr;6:105–112. [PMC free article] [PubMed]
  • Halls J. Bowel content shift during normal defaecation. Proc R Soc Med. 1965 Nov;58(11 Pt 1):859–860. [PubMed]
  • HANSKY J, CONNELL AM. Measurement of gastrointestinal transit using radioactive chromium. Gut. 1962 Jun;3:187–188. [PMC free article] [PubMed]
  • Wall GM, Kenny JC, Fan TY, Schafer C, Ready MA, Baker JK, Ritter P, Scott BS. Analysis of 3- and 4-monopivaloylepinephrine, degradation products in dipivefrin hydrochloride drug substance and ophthalmic formulations. J Pharm Biomed Anal. 1992 Jun;10(6):465–471. [PubMed]
  • Hinton JM, Lennard-Jones JE, Young AC. A ne method for studying gut transit times using radioopaque markers. Gut. 1969 Oct;10(10):842–847. [PMC free article] [PubMed]
  • Holdstock DJ, Misiewicz JJ, Waller SL. Observations on the mechanism of abdominal pain. Gut. 1969 Jan;10(1):19–31. [PMC free article] [PubMed]
  • Hersh JH, Cole TR, Bloom AS, Bertolone SJ, Hughes HE. Risk of malignancy in Sotos syndrome. J Pediatr. 1992 Apr;120(4 Pt 1):572–574. [PMC free article] [PubMed]
  • Misiewicz JJ. Measurement of intraluminal pressures: radiotelemetry, design of manometric studies, and computer analysis of records. Am J Dig Dis. 1968 May;13(5):389–396. [PubMed]
  • Misiewicz JJ, Waller SL, Fox RH, Goldsmith R, Hunt TJ. The effect of elevated body temperature and of stress on the motility of stomach and colon in man. Clin Sci. 1968 Feb;34(1):149–159. [PubMed]
  • Misiewicz JJ, Waller SL, Healy MJ, Piper EA. Computer analysis of intraluminal pressure records. Gut. 1968 Apr;9(2):232–236. [PMC free article] [PubMed]
  • Misiewicz JJ, Waller SL, Kiley N. Effect of oral prostaglandin E1 on intestinal transit in man. Lancet. 1969 Mar 29;1(7596):648–651. [PubMed]
  • RAMORINO ML, COLAGRANDE C. INTESTINAL MOTILITY: PRELIMINARY STUDIES WITH TELEMETERING CAPSULES AND SYNCHRONIZED FLUOROCINEMATOGRAPHY. Am J Dig Dis. 1964 Jan;9:64–71. [PubMed]
  • RAMSAY GS. PROGRESS OF A MARKER IN THE LARGE INTESTINE. Dis Colon Rectum. 1965 Jan-Feb;8:74–75. [PubMed]
  • Ritchie JA. Colonic motor activity and bowel function. I. Normal movement of contents. Gut. 1968 Aug;9(4):442–456. [PMC free article] [PubMed]
  • Ritchie JA. Colonic motor activity and bowel function. II. Distribution and incidence of motor activity at rest and after food and carbachol. Gut. 1968 Oct;9(5):502–511. [PMC free article] [PubMed]
  • RITCHIE JA, ARDRAN GM, TRUELOVE SC. Motor activity of the sigmoid colon of humans. A combined study by intraluminal pressure recording and cineradiography. Gastroenterology. 1962 Dec;43:642–668. [PubMed]
  • Rosswick RP, Stedeford RD, Brooke BN. New methods of studying intestinal transit times. Gut. 1967 Apr;8(2):195–196. [PMC free article] [PubMed]
  • THOMSON JA, BOYLE JA, MCGIRR EM, TILSTON RG. CLINICAL TRIAL OF MODIFIED GAMMA CAMERA FOR THYROID SCANNING. Lancet. 1964 Oct 3;2(7362):714–716. [PubMed]

Articles from Gut are provided here courtesy of BMJ Publishing Group