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Gut. 1993 April; 34(4): 562–564.
PMCID: PMC1374322

Cap polyposis--an unusual cause of diarrhoea.


'Cap polyposis' is a poorly recognised condition with distinct clinical, sigmoidoscopic, and pathological features that may be confused with other inflammatory conditions of the large intestine including pseudomembranous colitis and idiopathic chronic inflammatory bowel disease. The pathogenesis is unknown but on the basis of the characteristic histological appearances, which are similar to those seen in situations where mucosal prolapse is the underlying mechanism, it has been suggested that the latter may be an important aetiological factor. Two cases are described. Histological features in the first (presence of intramucosal elastin) and clinical features in the second (rectal prolapse) support the above hypothesis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • du Boulay CE, Fairbrother J, Isaacson PG. Mucosal prolapse syndrome--a unifying concept for solitary ulcer syndrome and related disorders. J Clin Pathol. 1983 Nov;36(11):1264–1268. [PMC free article] [PubMed]
  • Shepherd NA. Pathological mimics of chronic inflammatory bowel disease. J Clin Pathol. 1991 Sep;44(9):726–733. [PMC free article] [PubMed]
  • Warren BF, Dankwa EK, Davies JD. 'Diamond-shaped' crypts and mucosal elastin: helpful diagnostic features in biopsies of rectal prolapse. Histopathology. 1990 Aug;17(2):129–134. [PubMed]

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