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From:
doi: 10.1128/IAI.74.1.794-797.2006

TABLE 1.

Survival of mice after intranasal challenge with B. anthracis spores

Group no.Immunization methodrPA (μg)Adjuvant (μg)% Survival on day 14 (no. of survivors/ no. challenged) (Pb)MTDc
1TCI20aHLT (4)50 (5/10) (0.007)3.5
2TCI20HLT (4)60 (6/10) (0.010)3.0
3TCI5HLT (4)20 (2/10) (0.281)2.9
4TCI1HLT (4)30 (3/10) (0.055)3.3
5TCI0.2HLT (4)60 (6/10) (0.010)3.0
6i.m.20aAlum10 (1/10)2.8
NonimmunizedNoneNoneNone10 (1/10)4.4
arPA was purchased from List Biological Laboratories.
bSignificance value represents a comparison of group 6 i.m. immunized mice versus TCI mice.
cMTD, mean time to death of animals that died, in days.