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Can Med Assoc J. 1985 April 15; 132(8): 919–923.
PMCID: PMC1345899

The 6-minute walk: a new measure of exercise capacity in patients with chronic heart failure


Cycle and treadmill exercise tests are unsuitable for elderly, frail and severely limited patients with heart failure and may not reflect capacity to undertake day-to-day activities. Walking tests have proved useful as measures of outcome for patients with chronic lung disease. To investigate the potential value of the 6-minute walk as an objective measure of exercise capacity in patients with chronic heart failure, the test was administered six times over 12 weeks to 18 patients with chronic heart failure and 25 with chronic lung disease. The subjects also underwent cycle ergometer testing, and their functional status was evaluated by means of conventional measures. The walking test proved highly acceptable to the patients, and stable, reproducible results were achieved after the first two walks. The results correlated with the conventional measures of functional status and exercise capacity. The authors conclude that the 6-minute walk is a useful measure of functional exercise capacity and a suitable measure of outcome for clinical trials in patients with chronic heart failure.

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Selected References

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  • Goldman L, Hashimoto B, Cook EF, Loscalzo A. Comparative reproducibility and validity of systems for assessing cardiovascular functional class: advantages of a new specific activity scale. Circulation. 1981 Dec;64(6):1227–1234. [PubMed]
  • Franciosa JA, Ziesche S, Wilen M. Functional capacity of patients with chronic left ventricular failure. Relationship of bicycle exercise performance to clinical and hemodynamic characterization. Am J Med. 1979 Sep;67(3):460–466. [PubMed]
  • Franciosa JA, Park M, Levine TB. Lack of correlation between exercise capacity and indexes of resting left ventricular performance in heart failure. Am J Cardiol. 1981 Jan;47(1):33–39. [PubMed]
  • Francis GS, Goldsmith SR, Cohn JN. Relationship of exercise capacity to resting left ventricular performance and basal plasma norepinephrine levels in patients with congestive heart failure. Am Heart J. 1982 Oct;104(4 Pt 1):725–731. [PubMed]
  • Benge W, Litchfield RL, Marcus ML. Exercise capacity in patients with severe left ventricular dysfunction. Circulation. 1980 May;61(5):955–959. [PubMed]
  • Franciosa JA, Cohn JN. Effect of isosorbide dinitrate on response to submaximal and maximal exercise in patients with congestive heart failure. Am J Cardiol. 1979 May;43(5):1009–1014. [PubMed]
  • Rubin SA, Chatterjee K, Ports TA, Gelberg HJ, Brundage BH, Parmley WW. Influence of short-term oral hydralazine therapy on exercise hemodynamics in patients with severe chronic heart failure. Am J Cardiol. 1979 Nov;44(6):1183–1189. [PubMed]
  • Maskin CS, Forman R, Klein NA, Sonnenblick EH, LeJemtel TH. Long-term amrinone therapy in patients with severe heart failure: drug-dependent hemodynamic benefits despite progression of disease. Am J Med. 1982 Jan;72(1):113–118. [PubMed]
  • Conradson TB, Rydén L. Sustained effect of hydralazine in long term treatment of CHF. Acta Med Scand Suppl. 1981;652:173–176. [PubMed]
  • McGavin CR, Gupta SP, McHardy GJ. Twelve-minute walking test for assessing disability in chronic bronchitis. Br Med J. 1976 Apr 3;1(6013):822–823. [PMC free article] [PubMed]
  • Mungall IP, Hainsworth R. Assessment of respiratory function in patients with chronic obstructive airways disease. Thorax. 1979 Apr;34(2):254–258. [PMC free article] [PubMed]
  • Butland RJ, Pang J, Gross ER, Woodcock AA, Geddes DM. Two-, six-, and 12-minute walking tests in respiratory disease. Br Med J (Clin Res Ed) 1982 May 29;284(6329):1607–1608. [PMC free article] [PubMed]
  • McGavin CR, Artvinli M, Naoe H, McHardy GJ. Dyspnoea, disability, and distance walked: comparison of estimates of exercise performance in respiratory disease. Br Med J. 1978 Jul 22;2(6132):241–243. [PMC free article] [PubMed]
  • Morgan AD, Peck DF, Buchanan DR, McHardy GJ. Effect of attitudes and beliefs on exercise tolerance in chronic bronchitis. Br Med J (Clin Res Ed) 1983 Jan 15;286(6360):171–173. [PMC free article] [PubMed]
  • Pardy RL, Rivington RN, Despas PJ, Macklem PT. Inspiratory muscle training compared with physiotherapy in patients with chronic airflow limitation. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):421–425. [PubMed]
  • Leitch AG, Morgan A, Ellis DA, Bell G, Haslett C, McHardy GJ. Effect of oral salbutamol and slow-release aminophylline on exercise tolerance in chronic bronchitis. Thorax. 1981 Oct;36(10):787–789. [PMC free article] [PubMed]
  • Leggett RJ, Flenley DC. Portable oxygen and exercise tolerance in patients with chronic hypoxic cor pulmonale. Br Med J. 1977 Jul 9;2(6079):84–86. [PMC free article] [PubMed]
  • McGavin CR, Gupta SP, Lloyd EL, McHardy GJ. Physical rehabilitation for the chronic bronchitic: results of a controlled trial of exercises in the home. Thorax. 1977 Jun;32(3):307–311. [PMC free article] [PubMed]
  • Belman MJ, Mittman C. Ventilatory muscle training improves exercise capacity in chronic obstructive pulmonary disease patients. Am Rev Respir Dis. 1980 Feb;121(2):273–280. [PubMed]
  • Sinclair DJ, Ingram CG. Controlled trial of supervised exercise training in chronic bronchitis. Br Med J. 1980 Feb 23;280(6213):519–521. [PMC free article] [PubMed]
  • Pardy RL, Rivington RN, Despas PJ, Macklem PT. The effects of inspiratory muscle training on exercise performance in chronic airflow limitation. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):426–433. [PubMed]
  • Woodcock AA, Gross ER, Geddes DM. Oxygen relieves breathlessness in "pink puffers". Lancet. 1981 Apr 25;1(8226):907–909. [PubMed]
  • Cockcroft AE, Saunders MJ, Berry G. Randomised controlled trial of rehabilitation in chronic respiratory disability. Thorax. 1981 Mar;36(3):200–203. [PMC free article] [PubMed]
  • Woodcock AA, Gross ER, Geddes DM. Drug treatment of breathlessness: contrasting effects of diazepam and promethazine in pink puffers. Br Med J (Clin Res Ed) 1981 Aug 1;283(6287):343–346. [PMC free article] [PubMed]
  • Guyatt GH, Pugsley SO, Sullivan MJ, Thompson PJ, Berman L, Jones NL, Fallen EL, Taylor DW. Effect of encouragement on walking test performance. Thorax. 1984 Nov;39(11):818–822. [PMC free article] [PubMed]

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