Search tips
Search criteria 


Logo of taosLink to Publisher's site
Trans Am Ophthalmol Soc. 1996; 94: 381–409.
PMCID: PMC1312105

A unification hypothesis of pigment dispersion syndrome.


PURPOSE: To synthesize recent findings regarding pigment dispersion syndrome in order to arrive at a hypothesis concerning the nature of an underlying genetic predisposition. METHODS: The literature on the subject was reviewed and analyzed. RESULTS: Eyes with pigment dispersion syndrome differ from normal in that they have a larger iris, a midperipheral posterior iris concavity that increases with accommodation, a more posterior iris insertion, increased iridolenticular contact that is reversed by inhibition of blinking, possibly an inherent weakness of the iris pigment epithelium, and an increased incidence of lattice degeneration of the retina. CONCLUSION: A gene affecting some aspect of the development of the middle third of the eye early in the third trimester appears at the present time to be the most likely cause.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (4.3M), or click on a page image below to browse page by page.

Articles from Transactions of the American Ophthalmological Society are provided here courtesy of American Ophthalmological Society