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J R Soc Med. 2003; 96(Suppl 43): 11–17.
PMCID: PMC1308782

Autonomic dysfunction in cystic fibrosis.

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Selected References

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  • Shields RW., Jr Functional anatomy of the autonomic nervous system. J Clin Neurophysiol. 1993 Jan;10(1):2–13. [PubMed]
  • McLeod JG. Autonomic dysfunction in peripheral nerve disorders. Curr Opin Neurol Neurosurg. 1992 Aug;5(4):476–481. [PubMed]
  • Davis PB, Kaliner M. Autonomic nervous system abnormalities in cystic fibrosis. J Chronic Dis. 1983;36(3):269–278. [PubMed]
  • Davis PB, Braunstein M, Jay C. Decreased adenosine 3':5'-monophosphate response to isoproterenol in cystic fibrosis leukocytes. Pediatr Res. 1978 Jun;12(6):703–707. [PubMed]
  • Greene DA, Sima AA, Stevens MJ, Feldman EL, Lattimer SA. Complications: neuropathy, pathogenetic considerations. Diabetes Care. 1992 Dec;15(12):1902–1925. [PubMed]
  • Hilz MJ, Marthol H, Neundörfer B. Diabetische somatische Polyneuropathie. Pathogenese, klinische Manifestationsformen und Therapie-Konzepte. Fortschr Neurol Psychiatr. 2000 Jun;68(6):278–288. [PubMed]
  • Dyck PJ, Zimmerman BR, Vilen TH, Minnerath SR, Karnes JL, Yao JK, Poduslo JF. Nerve glucose, fructose, sorbitol, myo-inositol, and fiber degeneration and regeneration in diabetic neuropathy. N Engl J Med. 1988 Sep 1;319(9):542–548. [PubMed]
  • Winegrad AI, Greene DA. Diabetic polyneuropathy: the importance of insulin deficiency, hyperglycemia and alterations in myoinositol metabolism in its pathogenesis. N Engl J Med. 1976 Dec 16;295(25):1416–1421. [PubMed]
  • Tesfaye S, Malik R, Harris N, Jakubowski JJ, Mody C, Rennie IG, Ward JD. Arterio-venous shunting and proliferating new vessels in acute painful neuropathy of rapid glycaemic control (insulin neuritis). Diabetologia. 1996 Mar;39(3):329–335. [PubMed]
  • Tuck RR, Schmelzer JD, Low PA. Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy. Brain. 1984 Sep;107(Pt 3):935–950. [PubMed]
  • Androne L, Gavan NA, Veresiu IA, Orasan R. In vivo effect of lipoic acid on lipid peroxidation in patients with diabetic neuropathy. In Vivo. 2000 Mar-Apr;14(2):327–330. [PubMed]
  • Stevens MJ. Nitric oxide as a potential bridge between the metabolic and vascular hypotheses of diabetic neuropathy. Diabet Med. 1995 Apr;12(4):292–295. [PubMed]
  • Cohen JA, Jeffers BW, Stabler S, Schrier RW, Estascio R. Increasing homocysteine levels and diabetic autonomic neuropathy. Auton Neurosci. 2001 Mar 23;87(2-3):268–273. [PubMed]
  • Lanng S, Thorsteinsson B, Lund-Andersen C, Nerup J, Schiøtz PO, Koch C. Diabetes mellitus in Danish cystic fibrosis patients: prevalence and late diabetic complications. Acta Paediatr. 1994 Jan;83(1):72–77. [PubMed]
  • Comi G, Corbo M. Metabolic neuropathies. Curr Opin Neurol. 1998 Oct;11(5):523–529. [PubMed]
  • Chaudhry V, Corse AM, O'Brian R, Cornblath DR, Klein AS, Thuluvath PJ. Autonomic and peripheral (sensorimotor) neuropathy in chronic liver disease: a clinical and electrophysiologic study. Hepatology. 1999 Jun;29(6):1698–1703. [PubMed]
  • Szalay F, Marton A, Keresztes K, Hermányi ZS, Kempler P. Neuropathy as an extrahepatic manifestation of chronic liver diseases. Scand J Gastroenterol Suppl. 1998;228:130–132. [PubMed]
  • Winkler G, Kempler P. A diabeteses és hepaticus neuropathiák patomechanizmusa. Orv Hetil. 2001 Nov 11;142(45):2459–2467. [PubMed]
  • Lugo-Olivieri CH, Soyer PA, Fishman EK. Cystic fibrosis: spectrum of thoracic and abdominal CT findings in the adult patient. Clin Imaging. 1998 Sep-Oct;22(5):346–354. [PubMed]
  • Vita G, Bellinghieri G, Trusso A, Costantino G, Santoro D, Monteleone F, Messina C, Savica V. Uremic autonomic neuropathy studied by spectral analysis of heart rate. Kidney Int. 1999 Jul;56(1):232–237. [PubMed]
  • Lancellotti L, D'Orazio C, Mastella G, Mazzi G, Lippi U. Deficiency of vitamins E and A in cystic fibrosis is independent of pancreatic function and current enzyme and vitamin supplementation. Eur J Pediatr. 1996 Apr;155(4):281–285. [PubMed]
  • Cynamon HA, Milov DE, Valenstein E, Wagner M. Effect of vitamin E deficiency on neurologic function in patients with cystic fibrosis. J Pediatr. 1988 Oct;113(4):637–640. [PubMed]
  • Sitrin MD, Lieberman F, Jensen WE, Noronha A, Milburn C, Addington W. Vitamin E deficiency and neurologic disease in adults with cystic fibrosis. Ann Intern Med. 1987 Jul;107(1):51–54. [PubMed]
  • Lagueny A. Neuropathies métaboliques et carentielles. Rev Prat. 2000 Apr 1;50(7):731–735. [PubMed]
  • Manzella D, Barbieri M, Ragno E, Paolisso G. Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes. Am J Clin Nutr. 2001 Jun;73(6):1052–1057. [PubMed]
  • Venter JC, Fraser CM, Harrison LC. Autoantibodies to beta 2-adrenergic receptors: a possible cause of adrenergic hyporesponsiveness in allergic rhinitis and asthma. Science. 1980 Mar 21;207(4437):1361–1363. [PubMed]
  • Fraser CM, Venter JC, Kaliner M. Autonomic abnormalities and autoantibodies to beta-adrenergic receptors. N Engl J Med. 1981 Nov 12;305(20):1165–1170. [PubMed]
  • Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA. Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies. N Engl J Med. 2000 Sep 21;343(12):847–855. [PubMed]
  • Schsnell O, Muhr D, Dresel S, Tatsch K, Ziegler AG, Haslbeck M, Standl E. Autoantibodies against sympathetic ganglia and evidence of cardiac sympathetic dysinnervation in newly diagnosed and long-term IDDM patients. Diabetologia. 1996 Aug;39(8):970–975. [PubMed]
  • Logan A. CNS growth factors. Br J Hosp Med. 1990 Jun;43(6):428–437. [PubMed]
  • Dyck PJ. Nerve growth factor and diabetic neuropathy. Lancet. 1996 Oct 19;348(9034):1044–1045. [PubMed]
  • Ewing DJ, Clarke BF. Autonomic neuropathy: its diagnosis and prognosis. Clin Endocrinol Metab. 1986 Nov;15(4):855–888. [PubMed]
  • Faerman I, Faccio E, Milei J, Nuñez R, Jadzinsky M, Fox D, Rapaport M. Autonomic neuropathy and painless myocardial infarction in diabetic patients. Histologic evidence of their relationship. Diabetes. 1977 Dec;26(12):1147–1158. [PubMed]
  • Page MM, Watkins PJ. Cardiorespiratory arrest and diabetic autonomic neuropathy. Lancet. 1978 Jan 7;1(8054):14–16. [PubMed]
  • Ewing DJ, Boland O, Neilson JM, Cho CG, Clarke BF. Autonomic neuropathy, QT interval lengthening, and unexpected deaths in male diabetic patients. Diabetologia. 1991 Mar;34(3):182–185. [PubMed]
  • Saul JP, Arai Y, Berger RD, Lilly LS, Colucci WS, Cohen RJ. Assessment of autonomic regulation in chronic congestive heart failure by heart rate spectral analysis. Am J Cardiol. 1988 Jun 1;61(15):1292–1299. [PubMed]
  • Ravits JM. AAEM minimonograph #48: autonomic nervous system testing. Muscle Nerve. 1997 Aug;20(8):919–937. [PubMed]
  • Ewing DJ, Clarke BF. Diagnosis and management of diabetic autonomic neuropathy. Br Med J (Clin Res Ed) 1982 Oct 2;285(6346):916–918. [PMC free article] [PubMed]
  • Ewing DJ, Martyn CN, Young RJ, Clarke BF. The value of cardiovascular autonomic function tests: 10 years experience in diabetes. Diabetes Care. 1985 Sep-Oct;8(5):491–498. [PubMed]
  • Watkins PJ, Mackay JD. Cardiac denervation in diabetic neuropathy. Ann Intern Med. 1980 Feb;92(2 Pt 2):304–307. [PubMed]
  • Watkins PJ, Mackay JD. Assessment of diabetic autonomic neuropathy using heart rate monitoring. Horm Metab Res Suppl. 1980;9:69–72. [PubMed]
  • Quadri R, Ponzani P, Zanone M, Maule S, La Grotta A, Papotti G, Valentini M, Matteoda C, Chiandussi L, Fonzo D. Changes in autonomic nervous function over a 5-year period in non-insulin-dependent diabetic patients. Diabet Med. 1993 Dec;10(10):916–919. [PubMed]
  • Töyry JP, Niskanen LK, Mäntysaari MJ, Länsimies EA, Uusitupa MI. Occurrence, predictors, and clinical significance of autonomic neuropathy in NIDDM. Ten-year follow-up from the diagnosis. Diabetes. 1996 Mar;45(3):308–315. [PubMed]
  • Low PA, Zimmerman BR, Dyck PJ. Comparison of distal sympathetic with vagal function in diabetic neuropathy. Muscle Nerve. 1986 Sep;9(7):592–596. [PubMed]
  • Piha SJ, Puukka P, Seppänen A. Short- and long-term reproducibility of cardiovascular tests of autonomic function in normal subjects. Clin Auton Res. 1991 Jun;1(2):115–118. [PubMed]
  • Lishner M, Akselrod S, Avi VM, Oz O, Divon M, Ravid M. Spectral analysis of heart rate fluctuations. A non-invasive, sensitive method for the early diagnosis of autonomic neuropathy in diabetes mellitus. J Auton Nerv Syst. 1987 May;19(2):119–125. [PubMed]
  • Freeman R, Saul JP, Roberts MS, Berger RD, Broadbridge C, Cohen RJ. Spectral analysis of heart rate in diabetic autonomic neuropathy. A comparison with standard tests of autonomic function. Arch Neurol. 1991 Feb;48(2):185–190. [PubMed]
  • Karemaker JM. Heart rate variability: why do spectral analysis? Heart. 1997 Feb;77(2):99–101. [PMC free article] [PubMed]
  • Akselrod S, Gordon D, Ubel FA, Shannon DC, Berger AC, Cohen RJ. Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science. 1981 Jul 10;213(4504):220–222. [PubMed]
  • Pomeranz B, Macaulay RJ, Caudill MA, Kutz I, Adam D, Gordon D, Kilborn KM, Barger AC, Shannon DC, Cohen RJ, et al. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol. 1985 Jan;248(1 Pt 2):H151–H153. [PubMed]
  • Akselrod S, Gordon D, Madwed JB, Snidman NC, Shannon DC, Cohen RJ. Hemodynamic regulation: investigation by spectral analysis. Am J Physiol. 1985 Oct;249(4 Pt 2):H867–H875. [PubMed]
  • Ziegler D, Laux G, Dannehl K, Spüler M, Mühlen H, Mayer P, Gries FA. Assessment of cardiovascular autonomic function: age-related normal ranges and reproducibility of spectral analysis, vector analysis, and standard tests of heart rate variation and blood pressure responses. Diabet Med. 1992 Mar;9(2):166–175. [PubMed]
  • Myers GA, Martin GJ, Magid NM, Barnett PS, Schaad JW, Weiss JS, Lesch M, Singer DH. Power spectral analysis of heart rate variability in sudden cardiac death: comparison to other methods. IEEE Trans Biomed Eng. 1986 Dec;33(12):1149–1156. [PubMed]
  • Lazzeri C, La Villa G, Laffi G, Vecchiarino S, Gambilonghi F, Gentilini P, Franchi F. Autonomic regulation of heart rate and QT interval in nonalcoholic cirrhosis with ascites. Digestion. 1997;58(6):580–586. [PubMed]
  • Kurata C, Uehara A, Sugi T, Ishikawa A, Fujita K, Yonemura K, Hishida A, Ishikawa K, Tawarahara K, Shouda S, et al. Cardiac autonomic neuropathy in patients with chronic renal failure on hemodialysis. Nephron. 2000 Apr;84(4):312–319. [PubMed]
  • Woo MA, Stevenson WG, Moser DK, Trelease RB, Harper RM. Patterns of beat-to-beat heart rate variability in advanced heart failure. Am Heart J. 1992 Mar;123(3):704–710. [PubMed]
  • Yeragani VK, Srinivasan K, Vempati S, Pohl R, Balon R. Fractal dimension of heart rate time series: an effective measure of autonomic function. J Appl Physiol (1985) 1993 Dec;75(6):2429–2438. [PubMed]
  • Pincus SM, Goldberger AL. Physiological time-series analysis: what does regularity quantify? Am J Physiol. 1994 Apr;266(4 Pt 2):H1643–H1656. [PubMed]
  • Stevens MJ. New imaging techniques for cardiovascular autonomic neuropathy: a window on the heart. Diabetes Technol Ther. 2001 Spring;3(1):9–22. [PubMed]
  • Aziz Q, Thompson DG. Brain-gut axis in health and disease. Gastroenterology. 1998 Mar;114(3):559–578. [PubMed]
  • Gershon MD, Erde SM. The nervous system of the gut. Gastroenterology. 1981 Jun;80(6):1571–1594. [PubMed]
  • Krarup T, Schwartz TW, Hilsted J, Madsbad S, Verlaege O, Sestoft L. Impaired response of pancreatic polypeptide to hypoglycaemia: an early sign of autonomic neuropathy in diabetics. Br Med J. 1979 Dec 15;2(6204):1544–1546. [PMC free article] [PubMed]
  • Chaudhuri KR, Thomaides T, Mathias CJ. Abnormality of superior mesenteric artery blood flow responses in human sympathetic failure. J Physiol. 1992 Nov;457:477–489. [PubMed]
  • Bittinger M, Barnert J, Wienbeck M. Autonomic dysfunction and the gastrointestinal tract. Clin Auton Res. 1999 Apr;9(2):75–81. [PubMed]
  • Arnbjörnsson E. Normal and pathological bowel sound patterns. Ann Chir Gynaecol. 1986;75(6):314–318. [PubMed]
  • Yoshino H, Abe Y, Yoshino T, Ohsato K. Clinical application of spectral analysis of bowel sounds in intestinal obstruction. Dis Colon Rectum. 1990 Sep;33(9):753–757. [PubMed]
  • Sugrue M, Redfern M. Computerized phonoenterography: the clinical investigation of a new system. J Clin Gastroenterol. 1994 Mar;18(2):139–144. [PubMed]
  • Lees CM, Smyth RL. The current management of cystic fibrosis. Int J Clin Pract. 2000 Apr;54(3):171–179. [PubMed]
  • Battle WM, Snape WJ, Jr, Alavi A, Cohen S, Braunstein S. Colonic dysfunction in diabetes mellitus. Gastroenterology. 1980 Dec;79(6):1217–1221. [PubMed]
  • Sakakibara R, Hattori T, Uchiyama T, Asahina M, Yamanishi T. Micturitional disturbance in pure autonomic failure. Neurology. 2000 Jan 25;54(2):499–501. [PubMed]
  • Ueda T, Yoshimura N, Yoshida O. Diabetic cystopathy: relationship to autonomic neuropathy detected by sympathetic skin response. J Urol. 1997 Feb;157(2):580–584. [PubMed]
  • Orr A, McVean RJ, Webb AK, Dodd ME. Questionnaire survey of urinary incontinence in women with cystic fibrosis. BMJ. 2001 Jun 23;322(7301):1521–1521. [PMC free article] [PubMed]
  • Smith SA, Dewhirst RR. A simple diagnostic test for pupillary abnormality in diabetic autonomic neuropathy. Diabet Med. 1986 Jan;3(1):38–41. [PubMed]
  • Smith SA, Smith SE. Evidence for a neuropathic aetiology in the small pupil of diabetes mellitus. Br J Ophthalmol. 1983 Feb;67(2):89–93. [PMC free article] [PubMed]
  • Cahill M, Eustace P, de Jesus V. Pupillary autonomic denervation with increasing duration of diabetes mellitus. Br J Ophthalmol. 2001 Oct;85(10):1225–1230. [PMC free article] [PubMed]
  • Davis PB, Shelhamer JR, Kaliner M. Abnormal adrenergic and cholinergic sensitivity in cystic fibrosis. N Engl J Med. 1980 Jun 26;302(26):1453–1456. [PubMed]

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