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J R Soc Med. 1996 July; 89(7): 401–402.
PMCID: PMC1295856

Seroprevalence of hepatitis B and C virus in two institutions caring for mentally handicapped adults.

Abstract

Hepatitis B virus infection is common in institutions caring for the mentally handicapped. Hepatitis B virus and hepatitis C virus share routes of transmission but the prevalence of hepatitis C virus infection in this population is unknown. We have tested 101 patients from two institutions in South-East England caring for adults with mental handicap for the presence of hepatitis C antibody, hepatitis B core antibody, and if necessary hepatitis B surface antigen. None tested positive for hepatitis C antibody, but 43 had hepatitis B core antibody of whom 14 were chronic carriers positive for hepatitis B surface antigen. Unlike hepatitis B virus, hepatitis C virus infection appears to be uncommon in UK institutions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Kingham JG, McGuire M, Paine DH, Wright R. Hepatitis B in a hospital for the mentally subnormal in southern England. Br Med J. 1978 Aug 26;2(6137):594–596. [PMC free article] [PubMed]
  • Szmuness W, Prince AM, Etling GF, Pick R. Development and distribution of hemagglutinating antibody against the hepatitis B antigen in institutionalized populations. J Infect Dis. 1972 Nov;126(5):498–506. [PubMed]
  • Alter MJ. Epidemiology of hepatitis C in the West. Semin Liver Dis. 1995 Feb;15(1):5–14. [PubMed]
  • Dusheiko GM, Smith M, Scheuer PJ. Hepatitis C virus transmitted by human bite. Lancet. 1990 Aug 25;336(8713):503–504. [PubMed]
  • Idéo G, Bellati G, Pedraglio E, Bottelli R, Donzelli T, Putignano G. Intrafamilial transmission of hepatitis C virus. Lancet. 1990 Feb 10;335(8685):353–353. [PubMed]
  • Levinson WM, Wormser GP, Forseter G, Calmann M, O'Brien TA. Hepatitis C virus seroprevalence in the developmentally disabled. Arch Intern Med. 1992 Nov;152(11):2309–2311. [PubMed]
  • Chaudhary RK, Perry E, Hicks F, MacLean C, Morbey M. Hepatitis B and C infection in an institution for the developmentally handicapped. N Engl J Med. 1992 Dec 31;327(27):1953–1953. [PubMed]
  • Martínez JL, del Hierro J, Camarero A, Medarde A, López MT, Latasa J. Estudio de la infección por virus de la hepatitis C en diferentes grupos de riesgo y en donantes de sangre. Enferm Infecc Microbiol Clin. 1991 Jun-Jul;9(6):345–350. [PubMed]
  • Krugman S, Overby LR, Mushahwar IK, Ling CM, Frösner GG, Deinhardt F. Viral hepatitis, type B. Studies on natural history and prevention re-examined. N Engl J Med. 1979 Jan 18;300(3):101–106. [PubMed]
  • Hollinger FB, Lin HJ. Community-acquired hepatitis C virus infection. Gastroenterology. 1992 Apr;102(4 Pt 1):1426–1429. [PubMed]
  • Mutimer DJ, Harrison RF, O'Donnell KB, Shaw J, Martin BA, Atrah H, Ala FA, Skidmore S, Hubscher SG, Neuberger JM, et al. Hepatitis C virus infection in the asymptomatic British blood donor. J Viral Hepat. 1995;2(1):47–53. [PubMed]
  • Esteban JI, Esteban R, Viladomiu L, López-Talavera JC, González A, Hernández JM, Roget M, Vargas V, Genescà J, Buti M, et al. Hepatitis C virus antibodies among risk groups in Spain. Lancet. 1989 Aug 5;2(8658):294–297. [PubMed]
  • Mortimer PP, Cohen BJ, Litton PA, Vandervelde EM, Bassendine MF, Brind AM, Hambling MH. Hepatitis C virus antibody. Lancet. 1989 Sep 30;2(8666):798–798. [PubMed]
  • Yano M. Advances in hepatitis C: sero-epidemiology and natural history. J Gastroenterol Hepatol. 1992 Sep-Oct;7(5):549–550. [PubMed]
  • Cunningham SJ, Cunningham R, Izmeth MG, Baker B, Hart CA. Seroprevalence of hepatitis B and C in a Merseyside hospital for the mentally handicapped. Epidemiol Infect. 1994 Feb;112(1):195–200. [PMC free article] [PubMed]

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