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J R Soc Med. 1996 January; 89(1): 53P–54P.
PMCID: PMC1295646

Congenital gingival granular cell tumour.


Congenital gingival granular cell tumours are rare lesions which have only occasionally been reported in the UK. Clinical features are of a benign lesion which occurs almost exclusively in newborn, Caucasian females and the anterior maxilla is the commonest site. Treatment consists of local excision and is curative.The terminology concerning this condition has been rather confused because of uncertainty regarding the histogenesis of these tumours and the similar histological appearance to adults granular cell myoblastoma occurring at other intraoral sites. The exact histogenesis of these tumours remains unsolved and they may be hamartomata. We describe a new case occurring within the UK, which illustrates many of the common clinical features of the condition, with an accompanying literature review.

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Selected References

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  • HANKEY GT. Congenital epulis (granular-cell myoblastoma or fibroblastoma) in a ten-weeks-premature infant. Proc R Soc Med. 1955 Dec;48(12):1015–1017. [PMC free article] [PubMed]
  • Welbury RR. Congenital epulis of the newborn. Br J Oral Surg. 1980 Dec;18(3):238–243. [PubMed]
  • Lack EE, Worsham GF, Callihan MD, Crawford BE, Vawter GF. Gingival granula cell tumors of the newborn (congenital "epulis"): a clinical and pathologic study of 21 patients. Am J Surg Pathol. 1981 Jan;5(1):37–46. [PubMed]
  • O'Brian FV, Pielou WD. Congenital epulis: its natural history. Arch Dis Child. 1971 Aug;46(248):559–560. [PMC free article] [PubMed]
  • Stewart CM, Watson RE, Eversole LR, Fischlschweiger W, Leider AS. Oral granular cell tumors: a clinicopathologic and immunocytochemical study. Oral Surg Oral Med Oral Pathol. 1988 Apr;65(4):427–435. [PubMed]

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